All about bones 1

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Bone membranes, development and the types of bone cells
Flora Wang
Flashcards by Flora Wang, updated more than 1 year ago
Flora Wang
Created by Flora Wang about 9 years ago
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Question Answer
Bones have two membranes, the ______________ and the ________________. Periosteum; endosteum
The periosteum lines the _______ surface, and the endosteum lines the ____________ ____________. Outer; Medullary cavity
The periosteum has two layers: the fibrous layer that contains ________ and the ________ layer that produces osteoblasts from progenitor cells. fibroblasts; cambium
___________ fibres connect the periosteum to the bone and they connected to the lamellae, which are the layers of bone. Sharpey's fibres
The periosteum has nerve endings. True or false True
What are the two types of bone development/ossification? intramembranous and endochondral
Intramembranous development occurs in ________ bones that originate from mesenchymal stem cells. flat
Intramembranous ossification begins with sheets of ____________ ____________ which contain osteoblasts. They secreate their matrix which later hardens and forms cancellous bone. connective tissue
Endochondral ossification forms __________ bone from _________ cartilage. compact; hyaline
(Endochondral ossification) The hyaline cartilage serves as a model for the shape bones need to be, but before ossification occurs, the ____________ must die. chondrocytes (a cell that has secreted the matrix of cartilage and becomes embedded in it.)
(Endochondral ossification) As the blood vessels enter the cartilage, the chondrocytes begin their death in the _________. diaphysis
(Endochondral ossification) As spongy bones begin to form, the _________ ____________ site is created. from this site, osteoblasts move to transform the cartilage to ________ bone. primary ossification site; spongy bone
(Endochondral ossification) Afterwards, osteoclasts destroy some of the new spongy bone for the _________ __________. Cartilage remains at the epiphysis and continues to increase in length. medullary cavity
After birth, ossification of the epiphysis at the ___________ ossification site begins, which is the same as in the diaphysis, expect the ______ bone is not broken down. secondary ossification site; spongy bone
The small region that remains between the diaphysis and epiphysis is called the epiphyseal plate
After early adulthood, bones cease to increase in length but do increase in ___________. diameter
Hormones secreted by the pituitary gland and ________ or ________ regulate bone growth. testes or ovaries
Vertebrate bones are composed of a substance called ___________________, which is made of calcium phosphate. hydroxyapatite
What are the three types of bone cells? Osteoblasts, osteoclasts and osteocytes.
____________ produce osteoid (a nonmineral matrix) that is eventually mineralized and harden to become bone. Osteoblasts
Osteocytes are mature bone cells that were once osteoblasts and are now trapped inside lacunae in the hardened bone.
Osteoclasts are bone destroyers that play an essential function in bone resorption.
Lacunae are small cavity within the bone matrix, containing an ____________, and from which ________ radiate and penetrate the adjacent lamellae to the canaliculi of neighboring lacunae, thus forming a system of cavities interconnected by minute canals. osteocyte; canaliculi
Canaliculi are small canals where extensions of __________ reach one another and are able to ____________________. osteocytes; communicate
Haversian canals are tubes that allow _____________ ____________ and ___________ to pass through bone. blood vessels and nerves
_____________ are large multinucleated cells, like macrophages, derived from the hematopoietis lineage. osteoclasts
Osteoclasts are characterized by a _______ edge where active resorption takes place with the secretion of bone-resorbing enzymes. ruffled
Our bone cells are responsible for bone ___________, ___________ and ___________. production, maintenance and modeling.
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