Entering the Cell

Description

Virology (Basics) Flashcards on Entering the Cell, created by gina_evans0312 on 14/04/2014.
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Flashcards by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312 about 10 years ago
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Resource summary

Question Answer
Recognition of Host Cells Suitable for Infection Normal cell receptors- specific ones allow it to recognize specific tissue
Targets for Primary Attachment Distal parts of protein, away from the cell membrane
Secondary Attachment Usually another component is bound as attachment proceeds, bringing it closer to the cell membrane
Receptor Mediated Endocytosis (Virus Type) Non-enveloped viruses
Receptor Mediated Endocytosis (Vesicle Formation) Clatherin coated pit forms virus containing vesicles
Receptor Mediated Endocytosis (Genome Exit) Vesicle is acidified, virion opens and genome enters cytoplasm
Fusion From Without (Virus Type) Enveloped Viruses
Fusion From Without (Genome Entry) Viral membrane fuses with cell membrane, virus enters cell in genome form
Fusion From Without (Envelope) Remains as a patch of protein on membrane- new virions pick them up as they leave the cell
Fusion From Within (Virus Type) Enveloped Virus
Fusion From Within (Vesicle Formation) Virus interacts with receptor, endocytic vesicle forms around whole virus
Fusion From Without (Genome Exit) Vesicle acidification causes vesicle & viral membranes to fuse, genome is released
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