Flashcards
Chapter 2 - Structure and Function of Cells of the Nervous System
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- 1sensory neuronneuron that detects changes in the external or internal environment and sends information about these changes to the central nervous system
- 2motor neuronneuron located within the central nervous system that controls the contraction of a muscle or the secretion of a gland
- 3interneuronneuron located within the nervous system
- 4Central Nervous System (CNS)the brain and spinal cord
- 5Peripheral Nervous System (PNS)The part of the nervous system outside the brain and spinal cord, including the nerves attached to the brain and spinal cord
- 6somacell body of a neuron, which contains the nucleus
- 7dendritea branched, treelike structure attached to the soma of a neuron that receives information from the terminal buttons of other neurons
- 8synapsejunction between the terminal button of an axon and the membrane of another neuron
- 9axonthe long, thin, cylindrical structure that conveys information from the soma of a neuron to its terminal buttons
- 10multipolar neurona neuron with one axon and many dendrites attached to its soma
- 11bipolar neurona neuron with one axon and one dendrite attached to its soma
- 12unipolar neurona neuron with one axon attached to its soma; the axon divides, with one branch receiving sensory information and the other sending the information into the central nervous system
- 13terminal buttonthe bud at the end of a branch of an axon; forms synapses with another neuron; sends information to that neuron
- 14neurotransmittera chemical that is released by a terminal button; has a excitatory or inhibitory effect on another neuron
- 15membranea structure consisting principally of lipid molecules that defines the outer boundaries of a cell and also constitutes many of the cell organelles
- 16cytoplasmthe viscous, semiliquid substance contained in the interior of a cell
- 17mitochondriaan organelle that is responsible for extracting energy for nutrients
- 18adenosine triphosphate (ATP)a molecule of prime importance to cellular energy metabolism; its breakdown liberates energy
- 19nucleusa structure in the central region of a cell, containing the chromosomes
- 20chromosomea strand of DNA, with associated proteins, found in the nucleus that carries genetic information
- 21deoxyribonucleic acid (DNA)a long, complex macromolecule consisting of two interconnected helical strands; along with associated proteins, strands of DNA constitute the chromosome
- 22genethe functional unit of the chromosome, which directs synthesis of one or more proteins
- 23cytoskeletonsupport structure formed of microtubules and other protein fibers that are linked to each other and form a cohesive mass that gives a cell its shape
- 24enzymea molecule that controls a chemical reaction, combining two substances or breaking a substance into two parts
- 25axoplasmic transportan active process by which substances are propelled along microtubules that run the length of the axon
- 26microtubulea long strand of bundles of protein filaments arranged around a hollow core; part of the cytoskeleton and involved in transporting substances from place to place within the cell
- 27gliathe supporting cells of the central nervous system
- 28astrocytea glial cell that provides support for neurons of the central nervous system, provides nutrients and other substances, and regulates the chemical composition of the extracellular fluid
- 29phagocytosisthe process by which cells engulf and digest other cells or debris caused by cellular degeneration
- 30oligodendrocytea type of glial cell in the central nervous system that forms myelin cheaths
- 31myelin sheatha sheath that surrounds axons and insulates them, preventing messages from spreading between adjacent axons
- 32mode of Ranviera naked portion of a myelinated axon, between adjacent oligodendroglia or Schwann cells
- 33microgliathe smallest of glial cells which act as phagocytes and protect the brain from invading microorganisms
- 34Schwann cella cell in the peripheral nervous system that is wrapped around a myelinated axon, providing one segment of its myelin sheath
- 35blood-brain barriera semipermeable barrier between the blood and the brain produced by the cells in the walls of the brain's capillaries
- 36area postremaa region of the medulla where the blood-brain barrier is weak; poisons can be detected there and can initiate vomiting
- 37electrodea conductive medium that can be used to apply electrical stimulation or to record electrical potentials
- 38microelectrodea very fine electrode, generally used to record activity of individual neurons
- 39membrane potentialthe electrical charge across a cell membrane; the difference in electrical potential inside and outside the cell
- 40oscilloscopea laboratory instrument that is capable of displaying a graph of voltage as a function of time on the face of a cathode ray tube
- 41resting potentialthe membrane potential of a neuron when it is not being altered by excitatory or inhibitory postsynaptic potentials; approximately -70mV in the giant squid axon
- 42depolarizationreduction (towards zero) of the membrane potential of a cell from its normal resting potential
- 43hyperpolarizationan increase in the membrane potential of a cell, relative to the normal resting potential
- 44action potentialthe brief electrical impulse that provides the basis for conduction of information along an axon
- 45threshold of excitationthe value of the membrane potential that must be reached to produce an action potential
- 46diffusionmovement of molecules from regions of high concentration to regions of low concentration
- 47electrolytean aqueous solution of a material that ionizes - namely, a soluble acid, base, or salt
- 48iona charged molecule that can be positively (cat-) or negatively (an-) charged
- 49electrostatic pressurethe active force between atomic particles charged with opposite signs or the repulsive force between atomic particles charged with the same sign
- 50intracellular fluidthe fluid contained within cells
- 51extracellular fluidbody fluids located outside of cells
- 52sodium-potassium transporta protein found in the membrane of all cells that extrudes sodium ions from and transports potassium ions into the cell
- 53ion channela specialized protein molecule that permits specific ions to enter or leave cells
- 54voltage-dependent ion channelan ion channel that opens or closes according to the value of the membrane potential
- 55all-or-none lawthe principle that once an action potential is triggered in an axon, it is propagated, without decrement, to the end of the fiber
- 56rate lawthe principle that variations in the intensity of a stimulus or other information being transmitted in an axon are represented by variations in the rate at which that axon fires
- 57saltatory conductionconduction of action potentials by myelinated axons. the action potential appears to jump from one node of Ranvier to the next
- 58postsynaptic potentialalterations in the membrane potential of a postsynaptic neuron, produced by liberation of neurotransmitter at the synapse
- 59binding sitethe location on a receptor protein to which a ligand binds
- 60liganda chemical that binds with the binding site of a receptor
- 61dendritic spinea small bud on the surface of a dendrite, with which a terminal button of another neuron forms a synapse
- 62presynaptic membranethe membrane of a terminal button that lies adjacent to the postsynaptic membrane and through which the neurotransmitter is released
- 63postsynaptic membranethe cell membrane opposite the terminal button in a synapse; the membrane of the cell that receives the message
- 64synaptic cleftthe space between the presynaptic membrane and the postsynaptic membrane
- 65synaptic vescilea small, hollow, beadlike structure found in terminal buttons; contains molecules of a neurotransmitters
- 66release zonea region of the interior of the presynaptic membrane of a synapse to which synaptic vesciles attach and release their neurotransmitters into the synaptic cleft
- 67postsynaptic receptora receptor molecule in the postsynaptic membrane of a synapse that contains a binding site for a neurotransmitter
- 68neurotransmitter-dependent ion channelan ion channel that opens when a molecule of a neurotransmitter binds with a postsynaptic receptor
- 69ionotropic receptora receptor that contains a binding site for a neurotransmitter and an ion channel that opens when a molecule of the neurotransmitter attaches to the binding site
- 70metabotropic receptora receptor that contains a binding site for a neurotransmitter that activates an enzyme that begins a series of events that opens an ion channel elsewhere in the cell's membrane when a molecule of the transmitter attaches to the binding site
- 71G proteina protein coupled to a metabotropic receptor that conveys messages to other molecules when a ligand binds with and activates the receptor
- 72second messengera chemical produced when a G protein activates an enzyme; carries a signal that results in the opening of the ion channel or causes other events to occur in the cell
- 73excitatory postsynaptic potention (EPSP)an excitatory depolarization of the postsynaptic membrane of a synapse caused by the liberation of a neurotransmitter by the terminal button
- 74inhibitory postsynaptic potential (IPSP)an inhibitory hyperpolarization of the postsynaptic membrane of a synapse caused by the liberation of a neurotransmitter by the terminal button
- 75reuptakethe reentry of a neurotransmitter just liberated by a terminal button back through its membrane, thus terminating the postsynaptic potential
- 76enzymatic deactivationthe destruction of a neurotransmitter by an enzyme after its release (Example: the destruction of acetylcholine by acetylcholinesterase
- 77acetylcholine (ACh)a neurotransmitter found in the brain, spinal cord, and parts of the peripheral nervous system that is responsible for muscular contraction
- 78acetylcholinestrase (AChE)The enzyme that destroys acetylcholine soon after it is liberated by the terminal buttons, thus terminating the postsynaptic potential
- 79neural integrationthe process by which inhibitory and excitatory postsynaptic potentials summate and control the rate of firing of a neuron
- 80autoreceptora receptor molecule located on a neuron that responds to the neurotransmitter released by that neuron
- 81presynaptic inhibitionthe action of a presynaptic terminal button in an axoaxonic synapse that reduces the amount of neurotransmitter released by the postsynaptic terminal button
- 82presynaptic facilitationthe action of a presynaptic terminal button in an axoaxonic synapse that increases the amount of neurotransmitter released by the postsynaptic terminal button
- 83neuromodulatora naturally secreted substance that acts like a neurotransmitter except that it is not restricted to the synaptic cleft but diffuses through the extracellular fluid
- 84peptidea chain of amino acids joined together by peptide bonds. Most neuromodulators, and some hormones, consist of these molecules
- 85hormonea chemical substance that is released by an endocrine gland and that has effects on target cells in other organs
- 86endocrine glanda gland that liberates its secretions into the extracellular fluid around capillaries and hence into the bloodstream
- 87target cellsthe type of cell that contains receptors for a particular hormone and is affected by the hormone
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- Flashcards for Chapter 2 of Foundations of Behavioral Neuroscience
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- Lorann Kearney
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