100974
Description
Mind Map by lucysavage176, updated more than 1 year ago
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Created by lucysavage176
almost 11 years ago
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Biological
- Family studies
- 1st degree relatives
- share 50%
- 18x more at risk
- Kendler
- Kendler
- share 50%
- inconclusive
- retrospective
- retrospective
- support
- Kety
- mothers with + without scizo
- matched pairs
- matched pairs
- group 1- diagnosed 16.2%
- gruop 2- 1.9%
- evaluation
- not rely on retrospective data
- memory
- memory
- genes vs environment
- reliablility of diagnosis
- others diagnosed on old system
- others diagnosed on old system
- not rely on retrospective data
- Kety
- 1st degree relatives
- Twin studies
- MZ 40%
- DZ 5.3%
- maudsly twin register
- share womb
- MZ 40%
- Adoption studies
- Finnish
- Tienari
- 112 schizo mothers
- 7% developed schizo
- 7% developed schizo
- 153 control
- 1.5%
- 1.5%
- separated before age 4
- poor communication in adopted families increaded risk
- Tienari
- Finnish
- Biochemical
- dopamine
- limbic system
- excess dopamine
- super-sensitivity
- scizo was induced in rats using amphetamines
- evaluation
- post mortems
- increase dopamine/receptor density
- not just scizo
- not only factor
- not only factor
- not just scizo
- PET scans
- causal?
- increase dopamine/receptor density
- drugs
- aleviate posative not negative symptoms
- most effective drugs affect serotonin
- aleviate posative not negative symptoms
- post mortems
- limbic system
- dopamine
- Diathesis stress
- predisposition
- trigger
- predisposition
- genetics cannot give full explaination
- 89% have no known relative with schizo
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