Autonomic Nervous System

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massey university
Samara Watts
Mind Map by Samara Watts, updated more than 1 year ago
Samara Watts
Created by Samara Watts over 6 years ago
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Resource summary

Autonomic Nervous System
  1. Adrenergic Pharmacology
    1. A Receptors
      1. A1- Adrenerrgic antagonists
        1. MOA: Bind to A1 receptors, blocking SNS response
          1. eg. prazosin
            1. use: hypertension, peripheral vascular disease
              1. AE: hypotension, frequent urination
        2. A1- Adrenergic agonists
          1. MOA: Bind to A1 receptors, stimulating SNS response
            1. eg. phenylephrine
              1. use: hypotension, nasal congestion, red eyes
                1. Adverse effects: hypertension, blurred vision
          2. A2- Agonists
            1. MOA: bind to A2 receptors, stopping release of catecholamines
              1. eg. clonidine
                1. use: hypertension
                  1. AE: dizziness, drowsiness, dry mouth/nose
          3. B Receptors
            1. B1- Adrenergic agonists
              1. MOA: binds to B1 receptors, stimulating SNS response
                1. eg. dobutamine
                  1. use: cardiac arrest, circulatory shock
                    1. AE: hypertension, tachycardia
              2. B2-Adrenergic agonists
                1. MOA: binds to B2 receptors, stimulating SNS response
                  1. eg. salbutamol, salmeterol
                    1. use: COPD, asthma
                      1. AE: tremor, tachycardia, ^ Blood glucose
                2. B-Antagonists/ Beta blockers
                  1. MOA: bind to B receptors, blocking SNS response
                    1. eg. carvedilol
                      1. use: cardiac disease, hypertension
                        1. AE: dizziness lethargy, insomnia
                3. Non selective Adrenergic agonists:
                  1. Bind to A and B receptors, stimulating SNS response
                    1. eg. adrenaline, noadrenaline, dopamine
                      1. Use: cardiac arrest, hypotension, shock
                4. Cholinergic Pharmacology
                  1. Muscarinic Receptors
                    1. Agonists
                      1. eg. acetylcholine
                        1. MOA: binds to muscarinic receptors, stimulating PNS response
                          1. use: miotics
                            1. AE: problems with eye accomadation
                      2. Antagonists
                        1. eg. atropine
                          1. MOA: bind to muscarinic receptors, Blocking PNS response
                            1. use: pre-med, dilation of pupils
                              1. AE: dry mouth, blurred vision
                      3. Nicotinic Receptors
                        1. Antagonists
                          1. eg. vecuronium
                            1. MOA: binds to nicotine receptors, blocking ACh binding
                              1. use: pre-med
                                1. AE: decreased BP
                          2. Agonists
                            1. eg. suxamethonium
                              1. MOA: mimicts ACh & binds to nicotinic receptors
                                1. use: short acting muscle relaxant
                                  1. AE: muscle spasm, hyperkalemia
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