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12012445
Inheritance
Description
Mind Map on Inheritance, created by Harsh Sahota on 27/01/2018.
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Mind Map by
Harsh Sahota
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Harsh Sahota
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Resource summary
Inheritance
Key words
Gene: A sequence of DNA that codes for a protein
Allele: different versions of the same gene
Dominant allele: when at least one allele is required for it to be expressed in the phenotype
Codominant allele: Where both alleles get expressed in the phenotype
Both A and B alleles are codominant, while o is recessive
When A and B are both present in the allele, they both get expressed
Recessive allele: when 2 alleles are required for the allele to be expressed
Genotype: The alleles on a genome
Phenotype: The characteristics an organism has as a result of the genotype
Locus: the position of a gene on a DNA Molecule
Homozygous: two alleles on both chromsomes
Heterozygous: 2 different alleles on the chromasomes
Monohybrid Inheritance
Dihybrid Inheritance
Linkage
Sex linkage
Sex-linked gene: When a gene is locate on the X or Y sex chromosomes
Males: XY
Females: XX
The Y chromosome is smaller than the X chromosome. The X Chromosome has more than 2000 genes while the Y chromosome has around 70
Sex linked disorders are more common in men as one faulty allele would cause a disorder, whereas in women would require two
Pedigree charts
You may be asked:
How is it recessive?
If person C had offspring with a normal female, What would be the offspring phenotypes?
How do you know that the faulty gene is on the X chromosome?
How do ya know the faulty gene is recessive?
Autosomal linkage
Autosome: All Chromosomes except for the sex chromosomes
Linked genes: 2 or more genes on the same chromosome
More linked = genes closer to each other on the chromosome
Linkage group: all genes on one chromosome
The genotypes are 'cut through the middle' to make the gametes'
its G + N On one chromosome, g + n on the other chromasome
However if crossing over occurs, the gametes would change
If the genes are more closely linked, Gametes are less likely to change as both genes could be swapped
Epistasis: When one gene masks the other
Example: mice
A= brown hair (agouti), a=black hair, B= produce melanin, b=no melanin production
If allele bb is present, the mouse will be white (albino), regardless of the gene A
if the mouse has allele Bb/BB, then melanin is produced and the colour of the mouse depends on gene A (Aa/AA = brown, aa=black)
This is an example of a recessive epistatic allele, but dominant epistatic alleles exist too
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