Clinical Trial

Clinical Trial

1. A prospective study comparing the effect and value of intervention(s) against a control in human being.

2. Essential elements of RCTS

   • Properly designed.
   • Unbiased treatment assignment (randomization).
   • Comparable test groups
   • Intervention and control arms
   • Follow-up for a specific outcome

3. Types of RCTS

   • Treatment trials
     • Pharmaceutical (treatment, prevention, biological, synthetic)
     • Device (prosthesis, sensory aids)
     • Procedure (surgery, laser, radiological)
     • Behavior change (smoking cessation, dietary modification, exercise).
     • Other (counseling, information provision).
   • Preventive trials (vaccine)
   • Diagnostic or screening tests
   • Trials of health care delivery