STI's

moumen mohamed
Mind Map by moumen mohamed, updated more than 1 year ago More Less
Pip Barton
Created by Pip Barton almost 8 years ago
rim  almorsy
Copied by rim almorsy about 1 year ago
Ahmed salah
Copied by Ahmed salah about 1 year ago
moumen mohamed
Copied by moumen mohamed about 1 year ago
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Description

Mind Map on STI's, created by moumen mohamed on 01/27/2020.

Resource summary

STI's
  1. SYPHILIS
    1. Treponoma Pallidum
      1. Gram negative
        1. Axial filaments
        2. Infection
          1. 1. Primary
            1. Chancre
              1. 4-6 wks
              2. 2. Secondary
                1. Fever
                  1. Rash
                    1. Liver infection
                      1. Swollen lymph nodes
                      2. 3.Tertiary
                        1. Gumma
                          1. Soft granular lesion
                          2. Antibiotic resistance
                            1. Immune complexes
                              1. Inflammation
                                1. Tissue destruction
                            2. Congenital
                              1. Skin lesions
                                1. Deafness
                                  1. Bone malformation
                                2. Diagnosis
                                  1. Microscopy
                                    1. Serological testing
                                    2. Treatment
                                      1. Chemotherapeutic
                                        1. Salvarsan
                                        2. Antibiotic
                                          1. Penicillin
                                        3. Immune evasion
                                          1. Cell wall
                                          2. X
                                          3. Trends
                                            1. Age
                                              1. Geography
                                                1. Sexual orientation
                                                2. CHLAMYDIA
                                                  1. Chlamydia Trachomatis
                                                    1. Diagnosis
                                                      1. PCR
                                                        1. Immunoassays
                                                        2. Treatment
                                                          1. Doxycycline
                                                          2. Gram negative
                                                            1. Small genome
                                                            2. 2 stage life cycle
                                                              1. Reticulate body
                                                                1. Replication
                                                                2. Elementary body
                                                                  1. Infection
                                                                  2. Cell cycle
                                                                    1. 1.Attachment
                                                                      1. OmpA binds heparan sulphate
                                                                      2. 2.Entry
                                                                        1. T3SS injects TARP
                                                                          1. Induces uptake
                                                                        2. 3.Primary differentiation
                                                                          1. EB to RB
                                                                          2. 4.Cell division
                                                                            1. Rapid multiplication
                                                                            2. 5.Effector secretion
                                                                              1. CPAF
                                                                                1. Degrade host TF's
                                                                                2. Chronic inflammatory response
                                                                                3. 6.Secondary differentiation
                                                                                  1. RB to EB (Intermediate form)
                                                                                    1. Chromosomal condensation
                                                                                      1. OMC formation
                                                                                        1. T3SS formation
                                                                                        2. 7.EB release
                                                                                      2. symptoms
                                                                                      3. GONORRHOEAE
                                                                                        1. Neisseria Gonorrhoeae
                                                                                          1. Gram negative
                                                                                          2. Diagnosis
                                                                                            1. Thayer Martin agar

                                                                                              Annotations:

                                                                                              • Vancomcin, inhibits gram positive Colistin, inhibits most gram neg
                                                                                              1. PCR
                                                                                              2. Treatment
                                                                                                1. 3rd gen cephalosporins
                                                                                                2. Virulence mechanisms
                                                                                                  1. Attachment pili
                                                                                                    1. Tight attachments
                                                                                                      1. Change surface proteins
                                                                                                        1. Recombination
                                                                                                          1. Transformation
                                                                                                            1. Gene exchange
                                                                                                            2. Antigenic variation
                                                                                                              1. Abberant recombination
                                                                                                              2. Sialylated lipopolysaccharide
                                                                                                                1. Resistant to complement and antibodies
                                                                                                                  1. Mimics host cell surface
                                                                                                              3. Symptoms
                                                                                                              4. Anatomy of FRT
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