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Action Potentials

lucyslade1 English

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Action Potentials

  1. Large, brief reversal of potential in axonal plasma membrane

  2. Initiated by stimulus, 3 factors

    • Depolarisation
      • Large concentration of Na+ ions cross plasma membrane
        • Once threshold reached (~-50mV)
          • Voltage-sensitive Na+ channels open allowing more Na+ to rush into cell
            • Produces large shift in polarity of neuron
              • Now an all or nothing response
    • Repolarisation
      • Once polarity reaches peak (~30-50mV)
        • Na+ channels are inactivated
          • K+ moves out of cell to repolarise it
            • Repolarise: Return to resting potential
    • Hyperpolarisation
      • Voltage of membrane reverses again
        • Goes slightly below resting potential (~-80mV)
          • Returns to resting baseline

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AP for ItN module
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lucyslade1
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