Glycogen Phosphorylase Structure (Without Phosphorylation)

gina_evans0312
Mind Map by , created almost 6 years ago

Year 2 Mind Map on Glycogen Phosphorylase Structure (Without Phosphorylation), created by gina_evans0312 on 10/23/2013.

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gina_evans0312
Created by gina_evans0312 almost 6 years ago
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Glycogen Phosphorylase Structure (Without Phosphorylation)
1 T Form
1.1 Inactive- Active site it buried within protein
1.1.1 Caused by
1.1.1.1 High ATP
1.1.1.2 High glucose-6-phosphate
1.1.1.3 Glucose (In the liver)
2 R Form
2.1 Active- Active site is acessable to glycogen
2.1.1 Caused by
2.1.1.1 AMP
2.1.1.2 Pi
2.1.1.3 Phosphorylation
3 Interface domain
3.1 Contains allosteric effector site
3.1.1 Where ATP/AMP binds
4 Active Site
4.1 Found in deep groove to prevent water entering
4.1.1 Entrance of water causes hydrolysis instead of phosphorylysis
4.1.2 Made of
4.1.2.1 Glycogen Storage
4.1.2.2 Interface
4.1.2.3 And C Terminus Domains
4.1.3 This deep groove is what causes the steric hinderence during cleavage

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