Environmental Toxicology 1-3

focuses on synthetic and natural pollutants on ecosystems
1. Silent Spring
  1. Chemical effects on ecosystems (DDT),
  2. North American environmental movement
Paracelsus
1. Dose makes the poison
2. toxicon
Environmental tragedies (Safety)
1. Minamata, Japan: MeHg
2. Kiev, Ukraine: Radioactive dust
3. Bhopal, India: Methyl Isocyanate (MIC)
Toxic Substances
1. Xenobiotic
2. Poison
3. Toxicant
4. Toxin
5. Efficacy (max)
6. Potency (range of increase)
7. Interactions
  1. Additive
  2. Synergistic
  3. Antagonistic
Exposure Tests
1. Acute
  1. Lethal dose
  2. PROS: estimate toxicity, target organs
    1. CONS: expensive, animal use, ethics
2. Subacute
3. Subchronic
  1. LOAEL and NOAEL
4. Chronic
  1. Best LOAEL and NOAEL
General Toxicity
1. Threshold vs. non-Threshold
2. Essential nutrients
  1. U-shaped (copper)
3. Hormesis
  1. J-shaped (alcohol)
4. Placebo
5. Nocebo

Resource summary

	Created by andrewmackrell25 over 11 years ago