Deep Venous Thrombosis

Description

National Heart, Lung, and Blood Institute. (2011). What is Deep Vein Thrombosis? Retrieved from http://www.nhlbi.nih.gov/health/health-topics/topics/dvt National Heart, Lung, and Blood Institute. (2011). What is Deep Vein Thrombosis? Retrieved from http://www.nhlbi.nih.gov/health/health-topics/topics/dvNational Heart, Lung, and Blood Institute. (2011). What is Deep Vein Thrombosis? Retrieved from http://www.nhlbi.nih.gov/health/health-topics/topics/dvt National Heart, Lung, and Blood
angelle.williams
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Resource summary

Deep Venous Thrombosis
  1. Pathophysiology
    1. Activation of blood coagulation
      1. Vein damage
        1. Venous Stasis
        2. Treatment
          1. Anticoagulant therapy
            1. Heparin, warfarin, Factor Xa inhibitors
              1. Fondaparinux, Rivaroxaban
                1. LMWH (enoxaparin),UFH
              2. Endovascular and Surgical Interventions
                1. Pharmacologic thrombolysis
                  1. Thrombolysis
                    1. Mechanical Thrombectomy
                      1. Angioplasty and stenting
                        1. IVC filter
                      2. Diagnosis
                        1. D-Dimer Testing
                          1. Coagulation profile
                            1. Ultrasonography
                              1. Diagnostic Imaging
                                1. CT scan
                                  1. Ventilation-Perfusion (V/Q) scan
                                  2. Pulmonary angiography
                                  3. Genetic Laboratory Testing
                                    1. Venography
                                      1. Wells Clincal Predictor
                                      2. Epidemiology
                                        1. Common cause of morbidity and mortality
                                          1. 1 out of 20 people develop DVT over lifetime
                                            1. Existing data suggest 80 cases per 100,000 annually
                                              1. Usually affects those over 40 years old
                                                1. Male-to-female ratio is 1:2:1( higher risk in males)
                                                  1. Increase with age in both sexes
                                            2. Exact incidence is not unknown due to limited studies
                                            3. Clinical Manifestations
                                              1. Positive Homans sign
                                                1. Pain, warmth, and edema of limb
                                                  1. Variable discoloration of limb
                                                2. "Silent" pulmonary embolism
                                                  1. Visible veins
                                                    1. Symptoms of PE
                                                      1. SOB, chest pain, rapid breathing, hemoptysis
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