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INTRO TO PATHOLOGY

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Bio Med and Pathology Mind Map on INTRO TO PATHOLOGY, created by aahughes on 17/04/2013.
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Mind Map by aahughes, updated more than 1 year ago
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INTRO TO PATHOLOGY
  1. Study of disease from a molecular level to effects on individual
    1. Goal is the identification of causes and prevention and treatment
      1. When cells are exposed to noxious physical, chemical they become injured
        1. cells respond to stimuli by getting bigger, smaller, proliferate or die
    2. CHARACTERISTICS OF DISEASE
      1. AETIOLOGY - cause
        1. PATHOGENISIS - mechanism causing disease
          1. CLINICAL MANIFESTATIONS - functional feature
            1. COMPLICATIONS/SEQUALE -systemic consequences
              1. PROGNOSIS - anticipated course ie cure or fate
                1. EPIDEMIOLOGY - population distrubution
      2. AETIOLOGY
        1. Genetic abnormalities
          1. Infective agent - bacteria, virus, fungi
            1. Chemicals, Radiation, Mechanical trauma
              1. Multifactorial causes
        2. DISEASE OF UNKNOWN CAUSE
          1. Classified as idiopathic, spontaneous, cryptogenic
            1. Arising from the body its self - process inside the body
          2. HOST PREDISPOSITION
            1. Nutritional status, genetic, pre-existing immunity
            2. PATHOGENISIS
              1. Common pathways:
                1. INFLAMMATION: tissue injury response to harmful stimuli
                  1. DEGENERATION:deterioration to cells in response to agents
                    1. CARCINOGENISIS:agents resulting in tumour formation
                      1. IMMUNE REACTIONS
              2. LATENT INTERVALS AND INCUBATION PERIOD
                1. LATENT: 2/3 decades - carcinogenisis
                  1. INCUBATION:days/weeks infectious bacteria or virus
                2. STRUCTURAL/FUNCTIONAL MANIFESTATIONS
                  1. Cause of disease produces clinical signs and symptoms
                    1. PATHOLOGICAL:are structural abnormalities evident through microscope
                    2. STRUCTURAL
                      1. TUMOURS:displace and destroy surrounding tissue
                        1. DEPOSITION OF ABNORMAL MATERIAL:amylodosis
                          1. ABNORMALLY SITED TISSUE: metastasis (spread)
                            1. LOSS OF TISSUE: ulcer or in an organ - infarction
                              1. OBSTRUCTION:asthma, vessel
                                1. RUPTURE OF HOLOW TUBE:aneurysm, perforation
                      2. FUNCTIONAL
                        1. EXCESSIVE SECRETION:of cell product ie hormone, mucus
                          1. INSUFFICIENT SECRETION:diabetes (insulin)
                            1. IMPAIRED NERVE FUNCTION:neuropathy
                              1. IMPAIRED MUSCLE FUNCTION:myopathy
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