Mind map
Adaptive Immune Response
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Adaptive Immune Response
It is specific
Immune components are activated only after infection start
Response magnitude is higher in the second and subsequent encounter
Immunological memory is stored
Lymphoid organs
- Primary
- Production sites of immune cells
- Maturation sites for immune cells in the absence of antigen
- Secondary
- Maturation sites for antigen-driven immune cells
- Primary
Lymphocyte
- T cells
- Mature in thymus
- B cells
- Mature in bone marrow
- Antigen- independence
- Have surface markers or receptors
- Bind to antigens
- Bind to receptors on other cells
- Transmit and receive messages
- Receptor molecules
- Major histocompatibility complex (MHS)
- Classes
- Class 1
- Expressed on all nucleated cells
- Class 2
- Antigen-presenting cells
- Class 3
- Protein associated with the complement system
- Class 1
- Classes
- Cluster of differentiation (CD)
- CD4
- Binds to MHS class 2
- CD8
- Binds to MHS class 1
- CD4
- Antigen-specific receptors
- Mature T and B cells
- Carry one specific type of receptors called clones
- To eliminate lymphocytes that recognize self-antigens
- T-cell receptors
- Supported by CD4 and CD8
- Immunoglobulins (Ig) or antibodies in B cells
- IgG, IgA, IgM, IgE, IgD
- Carry one specific type of receptors called clones
- Mature T and B cells
- Major histocompatibility complex (MHS)
- Have surface markers or receptors
- T cells
T-cell Response
- T helper cell
- Activate other cells
- Memory T cell
- Store immunological memory
- Regulatory T cells
- Prevent excessive inflammation and autoimmunity
- Cytotoxic T cells
- Attack infected, cancerous and foreign cells
- T helper cell
B cells
- Memory B cells
- Store immunological memory
- Regulatory B cells
- Prevent excessive inflammation and autoimmunity
- Plasma cells
- Launch antibodies
- Neutralisation
- Opsonisation
- Agglutination
- Antitoxin action
- Launch antibodies
- Memory B cells