Urinary Tract Infections

Description

Mind Map on Urinary Tract Infections, created by Zulhilmi Zainal on 27/03/2014.
Zulhilmi Zainal
Mind Map by Zulhilmi Zainal, updated more than 1 year ago
Zulhilmi Zainal
Created by Zulhilmi Zainal about 10 years ago
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Resource summary

Urinary Tract Infections
  1. women
    1. bacteria ascend the urethra to the bladder
      1. Escherichia coli
        1. commonest
        2. Staphylococcus saprophyticus
          1. younger women
          2. types
            1. Complicated
              1. urinary instrumentation, anatomic abnormalities, and obstruction of urine flow
              2. Uncomplicated
                1. young women
                  1. Sexual activity
                2. Upper Tract Disease
                  1. pyelonephritis
                    1. Symptoms
                      1. Fever
                        1. Nausea, vomiting
                          1. Pain in the costovertebral areas
                            1. dysuria
                            2. therapy
                              1. intravenous antibiotics for 10-14 days
                                1. large amount of water
                                2. kidney parenchyma
                                  1. PATHOGENESIS
                                    1. hematogenous
                                      1. S. aureus, Salmonella species, P. aeruginosa, and Candida species
                                      2. ascending route
                                        1. E. coli, P. mirabilis ,K. pneumoniae
                                  2. lower Tract Disease
                                    1. Cystitis
                                      1. Dysuria, urinary urgency and frequency, bladder fullness/discomfort
                                        1. Most common UTI
                                          1. Bacterial
                                            1. Most common
                                              1. 1st e.coli, 2nd Staphylococcus saprophyticus
                                              2. Viral
                                                1. Adenoviruses
                                                  1. Severe bladder irritation , sometimes hemorrhagic
                                                  2. self limited
                                                  3. Fungal
                                                    1. immunocompromised
                                                      1. Candida and aspergillus
                                                        1. Amphotericin , ketoconazole
                                                    2. parasite
                                                      1. Urinary Schistosomiasis
                                                        1. schistosoma haematobium
                                                          1. haematuria and fibrosis
                                                            1. Praziquanetel
                                                        2. UTI in children
                                                          1. enuresis, fever, poor weight gain
                                                          2. Urethritis
                                                            1. sexual activity
                                                              1. Dysuria
                                                                1. purulent discharge
                                                                  1. gonococcal
                                                                  2. Treatment
                                                                    1. Ceftriaxone - Gonorrhea
                                                                  3. Acute urethral syndrome
                                                                    1. NOT caused by a urinary tract infection
                                                                      1. Symptoms are similar to those caused by a urinary tract infection
                                                                    2. ACUTE Prostatitis
                                                                      1. bacterial infection
                                                                        1. Men ages 20 - 35 who have multiple sexual partners
                                                                          1. medical emergency
                                                                        2. Asymptomatic bacteriuria
                                                                          1. significant number of bacteria in the urine that occurs without usual symptoms.
                                                                            1. WBC count in urine elevated
                                                                        3. others
                                                                          1. Perinephric abcess
                                                                            1. start in the bladder> kidney > area around the kidney.
                                                                              1. infection
                                                                                1. Stones
                                                                                  1. drain pus & IV antibiotics
                                                                                  2. Genitourinary Tuberculosis
                                                                                    1. Sterile pyuria
                                                                                    2. Renal TB
                                                                                      1. Formation of granulomas > caseation and tissue destruction.
                                                                                        1. Calcification and scarring
                                                                                        2. Tuberculous ureteritis
                                                                                          1. Results from renal tuberculosis
                                                                                            1. Scarring > obliteration of the ureter
                                                                                          2. Tuberculous cystitis
                                                                                            1. Fibrosis and fistulas
                                                                                              1. Gulf-hole orifice
                                                                                              2. UTI in Women
                                                                                                1. Short urethra
                                                                                                  1. Estrogen deficiency
                                                                                                    1. proximity to anus
                                                                                                    2. Bacterial Virulence Factors
                                                                                                      1. Flagella- enhanced motility
                                                                                                        1. hemolysin -> cell lysis
                                                                                                          1. fimbriae & adhesin -> adhere to cells
                                                                                                          2. treatment
                                                                                                            1. anti- pathogens
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