Laboratory tests

Amoridei
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Amoridei
Created by Amoridei about 7 years ago
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4/21/14 Lab tests ppt

Resource summary

Laboratory tests
1 Diagnostic Testing
1.1 add information to pt database
1.2 Screening
1.2.1 identify risk factors
1.2.2 asymptomatic patients
1.3 Diagnosis
1.3.1 Est. of exclude press. of disease
1.3.2 symptomatic patients
1.4 Patient Management
1.4.1 evaluate severity of disease
1.4.2 estimate prognosis
1.4.3 monitor course of disease
1.4.3.1 progression
1.4.3.2 stability
1.4.3.3 resolution
1.4.4 Detect disease recurrence
1.4.5 Select Meds and adjust therapy
1.5 Performance of Diagnostic Tests
1.5.1 Preparation
1.5.1.1 Test
1.5.1.1.1 specimen
1.5.1.1.1.1 most crucial element for properly conducted test
1.5.1.2 Patient
1.5.1.2.1 Fasting
1.5.1.2.1.1 glucose
1.5.1.2.1.2 triglyceride
1.5.1.2.2 posture
1.5.1.2.2.1 renin
1.5.1.2.3 Na intake
1.5.1.2.3.1 aldosterone
1.5.1.2.4 Strenuous Exercise
1.5.1.2.4.1 creatine kinase level may be abnormal
1.5.2 Specimen Collection
1.5.2.1 patient ID
1.5.2.1.1 2 identifiers
1.5.2.2 labeling
1.5.2.2.1 collection time
1.5.2.3 Avoid
1.5.2.3.1 drawing around IV line
1.5.2.3.1.1 fluid/drugs
1.5.2.3.2 Excessive tourniquet time
1.5.2.3.2.1 Hemoconcentration
1.5.2.3.2.2 increased Ca
1.5.2.3.3 Delay in delivery to lab
1.5.2.4 cell lysis
1.5.2.4.1 increased K and Lactate dehydrogenase
1.5.2.5 Special Handling and Storage
1.5.2.5.1 ABG
2 Diagnostic Test Characterisitcs
2.1 Reference Interval
2.1.1 REPORT QUANTITATIVE RESULTS
2.1.2 Method and laboratory specific
2.1.3 rep results of 95% of pop presumed to be healthy
2.1.4 consider in light of patient parameters
2.2 Accuracy
2.2.1 correspond to true value
2.2.2 maximize
2.2.2.1 calibrate equipment
2.2.2.2 external proficiency testing
2.2.3
2.3 Precision
2.3.1 measure of reproducibility when repeated on same sample
2.3.2 IDEAL TEST IS BOTH ACCURATE AND PRECISE
2.4 Interfering factors
2.4.1 considered in interpretation of results
2.4.1.1 external
2.4.1.1.1 medications
2.4.1.2 Internal
2.4.1.2.1 abnormal physiologic states
2.5 Sensitivity
2.5.1 ability to detect disease
2.5.1.1 90% sensitive test gives positive results in 90% of diseased patients
2.5.1.1.1 10% of diseased patients will get negative results, aka false negative
2.5.1.1.2 high sensitivity
2.5.1.1.2.1 useful to exclude diagnosis
2.5.2 % of patients w/ + test for disease
2.6 specificity
2.6.1 ability to detect absence of a disease
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