Notes
Martinez and Kesner (1991)
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AIM:
- determine the role of the neurotransmitter acetylcholine on memory.
METHODS:
- Rats were trained to go through a maze and get to the end where they received food
- After rats were able to do this, he injected:
1st group - scopolamine, which blocks acetylcholine receptor sites.
2nd group - physostigmine, blocks production of cholinesterase (does 'clean-up' of acetylcholine from synapse and returns neuron to its 'resting state')
3rd group - control (no injections)
RESULTS:
- scopolamine - slower at finding way around maze and made more errors than control/physostigmine group.
- physostigmine - ran faster compared to both groups and made fewer wrong turns.
CONCLUSION:
- Acetylcholine played an important role in creating memory
- Overall, it can be seen that neurotransmitters do affect human behaviour in a variety of ways.
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- the role of neurotransmitters in learning and memory
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