Flashcards
Phenothiazine and butyrophenones derivatives
Flashcards do conjunto (6)
- 1Primary purpose1. tranquilizer
2. potentiates analgesia - 2Secondary uses1. anti-emetic (esp. 15 min b4 opioids)
2. anti-histamine
3. anti-arrhythmic
4. anti-sympathetic - 3mode of action1. depression of reticular activating system
2. anti-dopaminergic activity
3. ↓ Mobilization of catecholamines = ↓sympathethetic tone - 4Side effect1. via Brain stem and alpha-1 antagonism:
vasodilation -> hypothermia and hypotension -> hypotension crisis.
2. ↓ platelet function
3. Synocope in Boxers - 5Pharmacokinetics1. lasts 4 to 8 hours; 48 hour residual effects
2.Metabolized by the liver - 6warningPotentiate the ventilatory and cardiovascular depressant effects of α2-agonists, opioids, and drugs used to produce general anesthesia
Informações
- Descrição
- Primary purpose, secondary use, Mode of action, Side effects
- Criado por
- Renee Robinson
- Visualizações
- 4
- Avaliação