Flashcards
Neurophysiology of Pain: Neuroregulators - Neurotransmitters (Excitatory)
Flashcards do conjunto (5)
- 1Prostaglandins1. Generated from the breakdown of phospholipids and cell membranes
2. Thought to increase sensitivity to pain - 2Bradykinin1. Released from plasma that leaks from surrounding blood vessels at the site of tissue injury
2. Binds to receptors on peripheral nerves, increasing pain stimuli
3. Binds two cells that cause a chain reaction producing prostaglandins - 3Substance P1. Found in pain neurons of dorsal horn (excitatory peptide)
2. Needed to transmit pain impulses from periphery to higher brain centers.
3. Causes vasodilation and edema - 4HistamineProduced by mast cells causing capillary dilation and increased capillary permeability
- 5SerotoninReleased from the brainstem and dorsal horn to inhibit pain transmission
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- Flashcards on Neurophysiology of Pain: Neuroregulators, created by Christian Cervan on 17/09/2016.
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- Christian Cervan
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