Cyt C Oxidase & F1F0

Descrição

Structural Basis for Biological Function (Membrane Proteins) Quiz sobre Cyt C Oxidase & F1F0, criado por gina_evans0312 em 18-12-2013.
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Quiz por gina_evans0312, atualizado more than 1 year ago
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Criado por gina_evans0312 mais de 10 anos atrás
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Resumo de Recurso

Questão 1

Questão
What is the main role of cytochrome aa3?
Responda
  • Takes e- from ubiquinol and reduces oxygen to water
  • Takes e- from ubiquinol and reduces oxygen to peroxide
  • Takes e- from cytochrome c and reduces oxygen to peroxide
  • Takes e- from cytochrome c and reduces oxygen to water

Questão 2

Questão
Complex IV contains how many subunits?
Responda
  • 12
  • 13
  • 14
  • 15

Questão 3

Questão
Complex IV doesn't transfer protons across the inner mitochondrial membrane
Responda
  • True
  • False

Questão 4

Questão
Which ions does it contain, and how many of each?
Responda
  • 2 Fe (in haeme groups) and 3 Cu (2 as a Cu-Cu binuclear centre, 1 as a binuclear Fe-Cu centre)
  • 2 Cu (in haeme groups) and 3 Fe (2 as a Fe-Fe binuclear centre, 1 as a binuclear Fe-Cu centre)
  • 2 Mg (in haeme groups) and 3 Cu (2 as a Cu-Cu binuclear centre, 1 as a binuclear Fe-Mg centre)

Questão 5

Questão
Cytochrome aa3 complex consists almost entirely of alpha helices
Responda
  • True
  • False

Questão 6

Questão
Put the following in order A- Cyt c B- CuA centre C- Cyt a D- Cyt a3-CuB centre E - Water •Transfer from cyt a3-CuB centre to oxygen
Responda
  • A-B-C-D-E
  • A-C-D-B-E
  • A-C-B-D-E

Questão 7

Questão
How many protons are pumped by complex 4, and how many are used to make water (per Oxygen molecule)?
Responda
  • 4 & 4
  • 4 & 2
  • 2 & 4

Questão 8

Questão
Which conformation of Complex IV has the low affinity for protons?
Responda
  • Conf. A
  • Conf. B
  • Conf. C

Questão 9

Questão
Protons bind to Complex IV during Conformation B
Responda
  • True
  • False

Questão 10

Questão
What happens during conformation B that lowers the Complex IV's affinity for protons?
Responda
  • Energy is put in
  • Energy is lost
  • The protein has an Fe group added

Questão 11

Questão
No question, just look at it and learn it
Responda
  • Okay?
  • Done

Questão 12

Questão
ATP synthase is found on the inner mitochondrial membrane
Responda
  • True
  • False

Questão 13

Questão
ATP synthase is divided into two sections, F1 & F0 Which is peripheral and which is integral?
Responda
  • F1 is peripheral F0 is integral
  • F0 is peripheral F1 is integral

Questão 14

Questão
Name the function of ATP synthase
Responda
  • ATP synthesis
  • ATP hydrolysis
  • ATP translocation
  • Proton translocation

Questão 15

Questão
If ATP is high, and the proton gradient is low, what will Complex V do instead?
Responda
  • Hydrolyse ATP
  • Synthesise GTP
  • Break itself down

Questão 16

Questão
Protons flow through F1 to power the ATP synthesis in F0
Responda
  • True
  • False

Questão 17

Questão
Name the subunits of F1
Responda
  • Alpha-Epsilon
  • A-E
  • 1-5

Questão 18

Questão
Which of the following subunit(s) are the largest in F1?
Responda
  • Alpha & Beta
  • Gamma & Delta
  • Beta and Gamma
  • Alpha and Epsilon

Questão 19

Questão
What is the role of the delta subunit in F1?
Responda
  • Stabiliser for the F1 head
  • ATP synthesis
  • Connets F1 too F0

Questão 20

Questão
The epsilon subunit of F0 connects the gamma to the C subunit
Responda
  • True
  • False

Questão 21

Questão
F0 contains how many subunits?
Responda
  • 2- A & B
  • 3- A, B & C
  • 2- Alpha & Beta

Questão 22

Questão
The F1 subunit is...
Responda
  • 8nm long
  • 18nm long
  • 12nm long
  • 90nm wide
  • 19nm wide
  • 9nm wide

Questão 23

Questão
The Y subunit of F1 is made of 2 beta sheets that have been bent, but are bound at the base
Responda
  • True
  • False

Questão 24

Questão
When the gamma subunit is in contact with a beta subunit, the ATP catalysis site is in it's _ formation
Responda
  • Open
  • Loose
  • Tight

Questão 25

Questão
A subunit contains ADP + Pi- what conformation is it in?
Responda
  • Loose
  • Tight
  • Open

Questão 26

Questão
Whilst the subunit is replacing ATP with ADP + Pi, the gamma subunit remains in plance
Responda
  • True
  • False

Questão 27

Questão
What order do the three conformations work in? Assume you start with the Loose formation
Responda
  • Loose-Tight-Open
  • Loose-Open-Tight

Questão 28

Questão
State the characteristics of the C subunit of F0
Responda
  • Small
  • Large
  • Hydrophobic
  • Hydrophilic
  • Integral
  • Peripheral

Questão 29

Questão
How many monomers make up the C subunit?
Responda
  • 8-12
  • 8-10
  • 4-10

Questão 30

Questão
The C subunit contains 3 rings of monomer
Responda
  • True
  • False

Questão 31

Questão
Why is there a variance across species of the number of monomers in the C subunit?
Responda
  • The more complex an organism, the more efficient the subunit
  • The more complex an organism, the less efficient the subunit
  • The larger the organism, the more subunits are required
  • Mammals have 8, birds have 12, all lesser animals and prokaryotes have 14 or more

Questão 32

Questão
More subunits require more protons to move them, so more subunits is less efficient
Responda
  • True
  • False

Questão 33

Questão
How is the A subunit described?
Responda
  • A proton half channel
  • A proton channel
  • A proton quarter channel

Questão 34

Questão
Protons passing through the A subunit...
Responda
  • Use it to enter the C subunit and exit to the cytoplasm
  • Use it to exit into C subunit and enter from the cytoplasm

Questão 35

Questão
Each subunit can hold 2 protons
Responda
  • True
  • False

Questão 36

Questão
The momevent of the protons around the C subunit powers what?
Responda
  • The movement of the gamma subunit
  • The conformational changes of the beta subunits
  • The attachment of the alpha subunits
  • The rotation of the delta subunit

Questão 37

Questão
The rotation of the F1 has been proved by attaching a microtubule filament to the F1 head and examining it under the microscope
Responda
  • True
  • False

Questão 38

Questão
Only the gamma subunit of the F1 complex rotates
Responda
  • True
  • False

Questão 39

Questão
How is the Alpha/Beta spheroid of F1 held in place?
Responda
  • B1 subunit
  • B2 subunit
  • Epsilon subunit
  • Delta subunit

Questão 40

Questão
For every _degree rotation, 1 molecule of ATP is produced
Responda
  • 90
  • 120
  • 180
  • 360

Questão 41

Questão
The mechanism of the gamma subunit causes an affinity change for ATP/ADP + Pi, driving the cycle
Responda
  • True
  • False

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