Quiz
Endocrine Block - THYROID (Week 3)
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Perguntas do quiz (10)
1Which connection allows communication between the hypothalamus and anterior pituitary gland?
- AHypophyseal portal system
- BHypothalamic hypophyseal tract
- CInfundibulum
- DSphenoid sinus cavity surrounding the pituitary gland
2Which connection allows communication between the hypothalamus and the posterior pituitary gland?
- AHypophyseal portal system
- BHypothalamic hypophyseal tract
- CInfundibulum
- DSphenoid sinus cavity surrounding the pituitary gland
3Which hormones are produced by the posterior pituitary gland?
- AOxytocin
- BADH
- CProlactin
- DTSH
- EFSH/LH
- FGH
- GACTH
4What is the correct order of the following anterior pituitary cell types, from most abundant to least abundant?
- ASomatotrophs (50%)
Lactotrophs (20%)
Corticotrophs (10-15%)
Gonadotrophs (10%)
Thyrotrophs (5%) - BSomatotrophs (50%)
Lactotrophs (20%)
Gonadotrophs (10-15%)
Corticotrophs (10%)
Thyrotrophs (5%) - CGonadotrophs (50%)
Lactotrophs (20%)
Corticotrophs (10-15%)
Thyrotrophs (10%)
Somatotrophs (5%) - DSomatotrophs (50%)
Lactotrophs (20%)
Corticotrophs (10-15%)
Thyrotrophs (10%)
Gonadotrophs (5%) - ECorticotrophs (50%)
Lactotrophs (20%)
Somatotrophs (10-15%)
Gonadotrophs (10%)
Thyrotrophs (5%)
- ASomatotrophs (50%)
5What are the 6 hormones released by the anterior pituitary gland?
- AADH
- BOxytocin
- CGH
- DFSH/LH
- EProlactin
- FACTH
- GTSH
6Which hypothalamic hormone stimulates the secretion of adrenocorticotrophic hormone (ACTH) from the anterior pituitary gland?
- ACorticotrophic releasing hormone (CRH)
- BThyroid releasing hormone (TRH)
- CGrowth hormone releasing hormone (GHRH)
- DGonadotrophin releasing hormone (GnRH)
- EDopamine
7Which test results would indicate cranial diabetes insipidus?
- AWater deprivation test - patients are desperate to drink; urine osmolality remains low
Response to ADH - DI improves - BWater deprivation test - patients are desperate to drink; urine osmolality stays low
Response to ADH - DI does not improve - CWater deprivation test - urine osmolality becomes high (i.e. concentrated)
Response to ADH - DI improves - DWater deprivation test - urine osmolality becomes high (i.e. becomes concentrated)
Response to ADH - DI does not improve
- AWater deprivation test - patients are desperate to drink; urine osmolality remains low
8What is the correct order for rates of functional pituitary adenomas?
- AProlactinomas (30%)
Cushing's disease (20%)
Acromegaly (15%)
TSHoma (<1%) - BProlactinomas (30%)
Cushing's disease (20%)
TSHomas (15%)
Acromegaly (<1%) - CAcromegaly (30%)
Cushing's disease (20%)
Prolactinomas (15%)
TSHoma (<1%) - DProlactinomas (30%)
TSHoma (20%)
Acromegaly (15%)
Cushing's disease (<1%)
- AProlactinomas (30%)
9Describe the process of thyroid hormone production:
1. Iodine is actively transported into the [blank_start]follicular thyroid cells[blank_end] via [blank_start]sodium iodide transporters[blank_end] on the basolateral side of the cell (this is called [blank_start]iodide trapping[blank_end])
2. Iodine diffuses to the luminal side of the cell
3. Iodine is transported into the follicle lumen by [blank_start]pendrin[blank_end], a membrane transporter
4. The follicle cells secrete [blank_start]thyroglobulin[blank_end] (containing ~70 [blank_start]tyrosine[blank_end] amino acids) into the lumen
5. Iodide ions undergo [blank_start]oxidation[blank_end] to form [blank_start]iodine[blank_end] via the action of the enzyme [blank_start]hydrogen peroxidase[blank_end]
6. [blank_start]Organification[blank_end] of the thyroglobulin molecule:
---Iodine binds to tyrosine amino acids within the thyroglobulin molecule via the action of [blank_start]thyroid peroxidase[blank_end]
---This forms [blank_start]monoiodotyrosine[blank_end]
---This undergoes further iodine binding to form [blank_start]diiodotyrosine[blank_end]
---MIT/DIT molecules are coupled to each other
7. If two DIT molecules couple together, [blank_start]T4 (thyroxine)[blank_end] is formed
8. If one MIT molecule couples with one DIT molecule, [blank_start]T3 (triiodothyronine)[blank_end] is formed- Afollicular thyroid cells
- Bsodium iodide transporters
- Ciodide trapping
- Dpendrin
- Ethyroglobulin
- Ftyrosine
- Goxidation
- Hiodine
- Ihydrogen peroxidase
- JOrganification
- Ktyrosine peroxidase
- Lmonoiodotyrosine (MIT)
- Mdiiodotyrosine (DIT)
- NT4 (thyroxine)
- OT3 (triiodothyronine)
10How much more concentrated is iodine in the thyroid than in the blood?
- Ax30
- Bx60
- Cx90
- Dx120
Informações
- Descrição
- Undergraduate MBChB Year 2 Quiz sobre Endocrine Block - THYROID (Week 3), criado por Melissa Denker em 30-11-2015.
- Autor
- Melissa Denker
- Idioma
- English
- Visualizações
- 33
- Etiquetas
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