Quiz
Molecular Chaperones in Bacteria, Yeast & Mammals
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Perguntas do quiz (22)
1What is the main role of a molecular chaperone?
- AAssist in the folding of other proteins
- BAssist in the unfolding of other proteins
- CAssist in the assembly of other proteins
- DAssist in the disassembly of other proteins
2Chaperone proteins are permanent parts of the proteins they fold
- AVerdadeiro
- BFalso
3Why are chaperone proteins necessary?
- ASome proteins have complex folding pathways,
- BSome proteins are inherently soluble
- CUseful for multimeric assembly
- DSo many proteins folding and interacting mean some need help
4Name the role of the domain highlighted in bacterial trigger factor
- APPIase domain
- BInteracts with polypeptide as it comes off the ribosome
- CBinds to L23 of the ribosome
5The highlighted domain of Bacterial trigger factor binds to L23 of the ribosome
- AVerdadeiro
- BFalso
6The bacterial ribosome and bacterial trigger factor form a complex, so the protein is folded as it comes off the ribosome
- AVerdadeiro
- BFalso
7The N-domain of the bacterial trigger factor bind to what subunit of what size ribosome?
- AL23
- BL24
- CL25
- D50s
- E40s
- F30s
8After the protein interacts with the T.F, it may interact with what proteins?
- ADNAK
- BDNAJ
- CDNAL
- DGro-EL
- EGro-ER
9What percent of proteins can fold unaided after interacting with DNAK/J?
- A70%
- B65%
- C75%
1010-15% of proteins need to use the lidded protein chaperone syastem
- AVerdadeiro
- BFalso
1115-18% of proteins need further _ interactions?
- ADNAK
- BDNAJ
- CGro-El
12Yeast has no trigger factor
- AVerdadeiro
- BFalso
13In yeast, what protein folding complex interacts with the proteins first?
- ANascent Polypeptide Associated Complex (NAC)
- BThe Ribosome Associated Complex (RAC)
- CCCT
14The RAC complex is made of which proteins?
- AZuptin
- BHsp40
- CSSZ
- DHsp70
15SSB is separated from the RAC but also chaperones protein folding
- AVerdadeiro
- BFalso
16The NAC is made of A and B homologues
- AVerdadeiro
- BFalso
17What is the role of the NAC?
- ABind to nascent proteins and prevent aggregation
- BBinds to nascent proteins and degrades them based on protein concentrations in the cell
- CBinds to nascent proteins and folds them
18Human cellss don't possess an NAC
- AVerdadeiro
- BFalso
19Humans have an hRAC rather than an RAC
- AVerdadeiro
- BFalso
20The human version of the RAC contains which two proteins?
- AMPP11
- BSSz
- CHsp70L1
- DSSb
21Name the lidded protein chaperone found in yeast and humans
- AGro-El
- BCCT
- CSSb
- DHsp70L1
22Name the circled sets of cytoplasmic folding proteins
- AHsp40/70- humans
- BHsp40/70- yeast
- CSSa/YDJ1- yeast
- DSsa/Ydj1- humans
- EPrefoldin
Informações
- Descrição
- Structural Basis for Biological Function (Protein Folding) Quiz sobre Molecular Chaperones in Bacteria, Yeast & Mammals, criado por gina_evans0312 em 20-12-2013.
- Autor
- gina_evans0312
- Idioma
- English
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- 674
- Etiquetas
- Avaliação
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