Quiz
Fluoride
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Perguntas do quiz (22)
1Which of these mechanisms allow fluoride to increase the resistance of teeth to acid attack?
- AReduce/inhibit enamel dissolving
- BPromoting remineralisation
- CChanging plaque ecology
- DReducing plaque acid production
- EIncreased enamel dissolution
2What is the acute lethal dose of fluoride?
- A32-64mg F / kg body weight
- B5 g F / kg body weight
- C32-64g F / kg body weight
- D5 mg F / kg body weight
3What is the toxic dose for fluoride?
- A5 mg F/ kg body weight
- B5 g F/ kg body weight
- C32-64mg F / kg body weight
- D32-64g F / kg body weight
4What are some clinical symptoms of fluoride poisoning?
- ANausea
- BDiarrhoea
- CConvulsions
- DCardiac arrhythmias
- EConjunctivitis
5Why might acute fluoride poisoning lead to cardiac dysrhythymia?
- AHypocalcemia / Hyperkalemia
- BHypercalcemia / Hypokalemia
- CHypernatremia / Hyperkalemia
- DHypercalcemia / Hyponatremia
6Skeletal fluorosis is sometimes mistaken for...
- AArthritis
- BOsteoporosis
- CParkinson's
- DHuntington's
7How does fluoride impair enamel formation?
- AInterferes with the ameloblasts in the early maturation phase leading to imperfect crystals / prisms
- BInterferes with the ameloblasts in the late maturation phase leading to imperfect crystals / prisms
- CLeads to imperfect collagen deposition by the ameloblasts leading to imperfect crystals / prisms
- DLeads to imperfect hydroxyapatite deposition by the odontoblasts leading to imperfect enamel crystals / prisms
8How does fluoride impair dentin formation?
- ALeads to impaired random collagen and hydroxyapatite deposition which is more susceptible to caries
- BLeads to impaired random hydroxyapatite deposition which is more susceptible to caries
- CLeads to impaired random collagen deposition which is more susceptible to caries
9Fluoride _________ mineralisation of bone, leading to heavy irregular mineralisation of bone.
- AStimulates
- BInhibits
1075-90% of fluoride is absorbed in the
- AStomach
- BDuodenum and Upper jejunum
- CLower jejunum and ileum
- DDuodenum only
11Fluoride is mostly absorbed by...
- APassive diffusion
- BActive transport
- CFacilitated diffusion
12Maternal and Foetal blood fluoride levels tend to be..
- ASimilar, therefore related.
- BCompletely different, therefore unrelated.
13The three phases of fluoride transport are:
1. Tissue fluid / soft tissue eq[blank_start]uilibration[blank_end] and dilution
2. Hard tissue deposition in tissues with high F [blank_start]affin.[blank_end]
3. [blank_start]Renal[blank_end] clearance of F which not deposited in skeleton- Auilibration
- Baffinity
- CRenal
14Fluoride accumulates in the soft tissues.
- AVerdadeiro
- BFalso
15Saliva and Tissue fluid have similar fluoride levels to blood plasma.
- AVerdadeiro
- BFalso
16Why does fluoride have such a high affinity for bone?
- AIt has a high affinity for hydroxyapatite in bone, preferentially forming fluorapatite.
- BIt has a high affinity for collagen in bone, preferentially forming fluoridated collagen.
- CIt has a high affinity for receptors in bone marrow which allow it to bind readily
17What is the half life of fluoride in someone who is not frequently exposed to F?
- A24 hrs
- B2 years
- C12 hrs
- D1 hr
18What factors might impact on renal clearance of fluoride?
- ADose of fluoride
- BPrevious exposure
- CFluid intake
- DCirrhosis
- EHalf life of fluoride
19Fluoride interferes with acid production by bacteria. How does it inhibit it?
- AInhibits the enolase enzyme involved in glycolysis (which ultimately produces lactic acid)
- BInhibits the alpha-ketoglutarate enzyme involved in glycolysis (which ultimately produces lactic acid)
- CInhibits the hexokinase enzyme involved in glycolysis (which ultimately produces lactic acid)
20Fluoride interferes with extracellular polysaccharide formation
- AVerdadeiro
- BFalso
21Fluoride decreases bacterial intracellular polysaccharide formation and glucose uptake.
- AVerdadeiro
- BFalso
22Fluoride does not affect cariogenicity but does decrease the amount of plaque formation.
- AVerdadeiro
- BFalso
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