Quiz
L35: Growth Hormone
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Perguntas do quiz (18)
1What percent of cells in the anterior pituitary are somatotrophs, which produce growth hormone?
- A50%
- B20%
- C70%
- D95%
2Choose the incorrect statements.
- A20% of the cells in the anterior pituitary gland are mammotrophs.
- B20% of the cells in the anterior pituitary gland are corticotrophs.
- C50% of the cells in the anterior pituitary gland are thyrotrophs.
- D5% of the cells in the anterior pituitary gland are somatotrophs.
3SS stands for:
- ASomatostatin
- BSomastatin
- CSomatostatic
4Somatotrophin is another name for growth hormone.
- AVerdadeiro
- BFalso
5Growth hormone has been able to be produced in vitro since 1979.
- AVerdadeiro
- BFalso
6Growth hormone is a [blank_start]peptide[blank_end] hormone. It is [blank_start]small[blank_end] (191 amino acids). The secretion of GH is [blank_start]pulsatile[blank_end] and has a [blank_start]daily[blank_end] rhythm which differs between males and females.
- Apeptide
- Bprotein
- Csmall
- Dlong
- Epulsatile
- Fcontinuous
- Gdaily
- Hhourly
7Growth hormone's half life in the blood is 20-25 minutes.
- AVerdadeiro
- BFalso
8Growth hormone is an exception for [blank_start]peptide[blank_end] hormones because it travels in the [blank_start]blood bound to a protein carrier[blank_end].
- Apeptide
- Bprotein
- Cblood bound to a protein carrier
- Dwithout a protein carrier
9Growth hormone releasing hormone neurons (GHRH neurons) in the [blank_start]hypothalamus[blank_end] are excited and release [blank_start]GHRH[blank_end] into the anterior pituitary gland where it stimulates [blank_start]somatotrophs[blank_end] to release growth hormone (GH). GH is released into the bloodstream where it stimulates [blank_start]insulin-like growth factor (IGF-1)[blank_end] production in the [blank_start]liver[blank_end].
IGF-1 feeds back to the hypothalamus where it [blank_start]inhibits[blank_end] more release of GHRH and stimulates [blank_start]somatostatin (SS)[blank_end] to inhibit release of [blank_start]GH[blank_end] by the anterior pituitary gland.- Ahypothalamus
- BGHRH
- Csomatotrophs
- Dinsulin-like growth factor (IGF-1)
- Eliver
- Finhibits
- Gsomatostatin (SS)
- HGH
10Choose the correct statements.
- AGrowth hormone release peaks during the night and settles down during the day, but is constantly spiking.
- BThe growth hormone secretion peak is less pronounced for males.
- CRelease of GH increases with age until it peaks at puberty.
- DThe puberty peak of GH release occurs earlier for females than males.
11Growth hormone is essential for [blank_start]brain development[blank_end] until around age 8, rapid growth of [blank_start]height[blank_end] in two separate periods, and growth of [blank_start]reproductive organs[blank_end] around puberty.
- Abrain development
- Bheight
- Creproductive organs
12Growth hormone receptor is a single molecule found in the membrane that does not require activation.
- AVerdadeiro
- BFalso
13Which of these is not a long term effect of growth hormone?
- AStimulation of bone and muscle growth
- BStimulation of mitogenesis (cell division) via IGF-1
- CStimulation of protein synthesis (in liver)
14Stimulation of mitogenesis via IGF-1 is a direct effect of growth hormone.
Stimulation of protein synthesis in muscle by is an indirect effect of growth hormone.- AVerdadeiro
- BFalso
15Short term effects of growth hormone are always direct.
- AVerdadeiro
- BFalso
16Choose the correct effects of GH on metabolism(short term effects).
- AIncrease in blood glucose by stimulating glucose synthesis (in
liver) - BIncrease in blood glucose by stimulating cellular uptake of glucose
- CDecrease in triglyceride breakdown in adipose tissue
- DFree fatty acid mobilisation in adipose tissue
- AIncrease in blood glucose by stimulating glucose synthesis (in
17Other hormones important for [blank_start]growth[blank_end] are thyroid hormones, insulin, cortisol, and estrogen/testosterone.
Thyroid hormone [blank_start]increases[blank_end] the basal metabolic rate and is essential for [blank_start]nervous system[blank_end] development.
Insulin and [blank_start]cortisol[blank_end] increase [blank_start]glucose[blank_end] metabolism.
Estrogen/testosterone are essential during [blank_start]puberty[blank_end].- Agrowth
- Bincreases
- Cnervous system
- Dglucose
- Epuberty
- Fcortisol
18Endocrine disorders can be due to too little GH ([blank_start]hyposecretion[blank_end]) or too much GH ([blank_start]hypersecretion[blank_end]).
An [blank_start]excess[blank_end] of GH can cause gigantism or acromegaly. Acromegaly is an excess of GH in [blank_start]adulthood[blank_end] which leads to thickening of [blank_start]bones[blank_end], and of soft tissues in the hands, feet and face. A [blank_start]deficiency[blank_end] can cause dwarfism.
Endocrine disorders can also result from an issue in the GH [blank_start]receptors[blank_end]. Hyposensitive receptors [blank_start]give little or no response[blank_end] to GH and the effects are similar to hyposecretion. Hypersensitive receptors [blank_start]overreact[blank_end] to GH and have similar effects to hypersecretion.- Ahyposecretion
- Bhypersecretion
- Cexcess
- Dadulthood
- Echildhood
- Fbones
- Gmuscles
- Hdeficiency
- Ireceptors
- Jgive little or no response
- Koverreact
Informações
- Descrição
- • Outline the sequence of events that results in the secretion of growth hormone. • Describe the metabolic effects of growth hormone on each type of target cell. • Describe the effects of growth hormone on human growth (during the growth years and after skeletal fusion) • Explain what occurs when there is too much or too little growth hormone secreted during childhood.
- Autor
- Mer Scott
- Idioma
- English
- Visualizações
- 116
- Etiquetas
- Avaliação
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