PHSI3012 03-2 Experimental Modelling of Carcinogenesis In Vivo

Description

Overview: - Analysis of cell phenotypes associated with cancer - Analysis of cancer cell phenotypes in vivo - Modelling metastasis - Mouse models of epithelial carcinogenesis - Survival and cross-sectional analysis - Modelling therapeutic treatment
Michael Jardine
Quiz by Michael Jardine, updated more than 1 year ago
Michael Jardine
Created by Michael Jardine over 6 years ago
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Resource summary

Question 1

Question
Define xenograft.
Answer
  • A graft of tissue taken from a donor of one species and grafted into a recipient of another species.
  • A graft of tissue taken from a donor of one species and grafted into a recipient of the same species.
  • A graft of tissue taken from a donor of one species, modified, then grafted back into the same donor as a recipient.

Question 2

Question
Longitudinal vs Cross-sectional analysis. Which is which?
Answer
  • Cross-sectional analysis = all mice sacrificed at same specific time point; Longitudinal analysis = mice sacrificed at ethical end point.
  • Cross-sectional analysis = mice sacrificed at ethical end point; Longitudinal analysis = all mice sacrificed at same specific time point.
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