Hormonal Secretion

Description

University Functional Anatomy and Embryology Quiz on Hormonal Secretion, created by Charlotte Jakes on 20/04/2020.
Charlotte Jakes
Quiz by Charlotte Jakes, updated more than 1 year ago
Charlotte Jakes
Created by Charlotte Jakes about 5 years ago
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Resource summary

Question 1

Question
Where do endocrine cells secrete their hormones into?
Answer
  • Target cells
  • Blood
  • Out of ducts
  • Glands

Question 2

Question
What is a neuroendocrine cell?
Answer
  • A cell that released hormones into the blood upon depolarisation
  • A cell that releases neurotransmitter into the blood upon depolarisation
  • A cell that releases hormones across the synaptic cleft upon depolarisation
  • A cell that releases hormones onto neighbouring cells upon depolarisation

Question 3

Question
What type of chemical signalling occurs when a cell targets itself?
Answer
  • Autocrine
  • Paracrine
  • Endocrine
  • Neuroendocrine

Question 4

Question
What type of chemical signalling occurs when a cell targets a neighbouring cell?
Answer
  • Paracrine
  • Autocrine
  • Endocrine
  • Neuroendocrine

Question 5

Question
What type of signalling occurs when a cell releases a signal into the blood to be carried to its distant target cell?
Answer
  • Paracrine
  • Autocrine
  • Endocrine
  • Neuroendocrine

Question 6

Question
Which of the following hormones are secreted by neurosecretory cells?
Answer
  • Protein/peptide hormones
  • Steroid hormones
  • Thyroid hormones
  • Catecholamines (adrenal hormones)

Question 7

Question
Which of the following hormones are secreted by epithelial tissues?
Answer
  • Protein/peptide hormones
  • Steroid hormones
  • Thyroid hormones
  • Catecholamines (adrenal hormones)

Question 8

Question
What gives a hormone a long half-life?
Answer
  • Being protein-bound in circulation
  • Being unbound to protein in circulation

Question 9

Question
The following questions will be about protein/peptide hormones. What must happen to preprohormones to form active prohormones?
Answer
  • Cleavage by proteolytic enzymes
  • Cleavage by low pH
  • Packaging into vesicles
  • Release by exocytosis

Question 10

Question
How are active protein/peptide hormones released?
Answer
  • Exocytosis stimulated by increase in cytosolic Ca2+
  • Exocytosis stimulated by increase in cytosolic K+
  • Holocrine secretion
  • Apocrine secretion

Question 11

Question
Are protein/peptide hormones protein-bound in circulation?
Answer
  • Yes
  • No

Question 12

Question
Which is true of protein hormones in circulation?
Answer
  • Long half-life
  • Short half-life

Question 13

Question
The following questions will be about steroid hormones. What are steroid hormones derived from?
Answer
  • Cholesterol
  • Proteins
  • Amines
  • DNA

Question 14

Question
Steroid hormones are lipid soluble.
Answer
  • True
  • False

Question 15

Question
Steroid hormones are stored in glands.
Answer
  • True
  • False

Question 16

Question
Are steroid hormones protein-bound in circulation?
Answer
  • Yes
  • No

Question 17

Question
Which is true of steroid hormones?
Answer
  • Long half-lives
  • Short half-lives

Question 18

Question
The following questions will be about amine hormones. Most amine hormones are derived from...?
Answer
  • Tyrosine
  • Phenylalanine
  • Glutamate
  • Aspartate

Question 19

Question
Thyroid hormones are amine hormones.
Answer
  • True
  • False

Question 20

Question
Which subtype of amine hormone is lipid-soluble?
Answer
  • Thyroid hormones
  • Catecholamines (adrenal hormones)

Question 21

Question
Which subtype of amine hormone is water-soluble?
Answer
  • Thyroid hormones
  • Catecholamines (adrenal hormones)

Question 22

Question
Which subtype of amine hormone is protein-bound in circulation, thus giving it a long half-life?
Answer
  • Thyroid hormones
  • Catecholamines (adrenal hormones)

Question 23

Question
Which subtype of amine hormone is not bound to protein in circulation, giving it a short half-life?
Answer
  • Thyroid hormones
  • Catecholamines (adrenal hormones)

Question 24

Question
Which subtype of amine hormones are stored intracellulary in secretory granules?
Answer
  • Thyroid hormones
  • Catecholamines (adrenal hormones)

Question 25

Question
What are eicosanoids?
Answer
  • Local chemical messengers
  • Steroid hormones
  • Protein hormones
  • Transcription regulators

Question 26

Question
What are eicosanoids derived from?
Answer
  • Arachidonic acid
  • Diacylglycerol
  • Inositol
  • PIP2

Question 27

Question
Which of the following is an example of an eicosanoid?
Answer
  • Prostaglandin
  • Catecholamine
  • Adrenaline
  • Parathyroid hormone

Question 28

Question
Which of the following hormones have intracellular receptors that alter gene transcription?
Answer
  • Steroid hormones
  • Thyroid hormones
  • Protein/peptide hormones
  • Glycoproteins
  • Catecholamines (adrenal hormones)

Question 29

Question
Which of the following hormones have membrane-bound receptors that initiate second-messenger pathways to change enzyme activity?
Answer
  • Steroid hormones
  • Thyroid hormones
  • Protein/peptide hormones
  • Glycoproteins
  • Catecholamines

Question 30

Question
Drag and drop the correct answers to describe the mechanism of steroid hormones. 1. The steroid hormone crosses the membrane as it is [blank_start]lipid[blank_end]-soluble. 2. The steroid hormone binds to its receptor in the cytosol or [blank_start]nucleus[blank_end]. 3. The receptor undergoes a [blank_start]conformational shape change[blank_end] that allows it to bind to DNA. 4. The receptor forms a [blank_start]dimer[blank_end] with another receptor unit and binds to DNA. 5. Binding alters [blank_start]transcription[blank_end] of target genes.
Answer
  • lipid
  • water
  • nucleus
  • Golgi apparatus
  • interstitium
  • conformational shape change
  • hydrolysis reaction
  • dimer
  • trimer
  • transcription
  • translation

Question 31

Question
Which of the following can control hormone secretion?
Answer
  • Change in plasma ion concentration
  • Change in plasma nutrient concentration
  • Neurotransmitter release from neurones contacting endocrine cells
  • Upstream hormone/paracrine agents acting on endocrine cells
  • Conscious effort
  • Repetitive limb movement
  • Lipolysis

Question 32

Question
Drag and drop the correct labels to describe the anatomy of the pituitary gland.
Answer
  • Paraventricular nucleus
  • Supraoptic nucleus
  • Neurosecretory cells
  • Optic chiasm
  • Median eminence
  • Infundibular stem
  • Hypophyseal portal vein
  • Pars tuberalis
  • Pars distalis
  • Pars nervosa
  • Posterior pituitary/neurohypophysis
  • Anterior pituitary/adenohypophysis

Question 33

Question
During the development of the pituitary gland, the outpouching of what will form the posterior pituitary/neurohypophysis?
Answer
  • Neuroectoderm of the diencephalon
  • Oropharynx ectoderm of the roof of the mouth

Question 34

Question
During the development of the pituitary gland, the outpouching of what will form the anterior pituitary/adenohypophysis?
Answer
  • Neuroectoderm of the diencephalon
  • Oropharynx ectoderm of the roof of the mouth

Question 35

Question
Drag and drop the correct labels to describe the development of the pituitary gland.
Answer
  • Neuroectoderm
  • Oropharynx ectoderm
  • Rathke's pouch
  • Developing sphenoid bone
  • Posterior pituitary/neurohypophysis
  • Anterior pituitary/adenohypophysis

Question 36

Question
Which of the following are secreted by the posterior pituitary/neurohypophysis?
Answer
  • ADH
  • Oxytocin
  • FSH
  • LH
  • ACTH

Question 37

Question
Drag and drop the correct answers to describe the secretion of hormones by the posterior pituitary gland/neurohypophysis. 1. Specific neural stimuli lead to the synthesis of hormones in [blank_start]cell bodies[blank_end] of [blank_start]hypothalamic[blank_end] nuclei. 2. The hormones are transported down the [blank_start]axons[blank_end] of [blank_start]neuroendocrine[blank_end] cells. 3. The hormones are stored in [blank_start]Herring bodies[blank_end] in the nerve terminals. 4. The hormones are released directly into the [blank_start]venous blood[blank_end] of the posterior pituitary.
Answer
  • cell bodies
  • hypothalamic
  • thalamic
  • cortical
  • axons
  • neuroendocrine
  • endocrine
  • paracrine
  • Herring bodies
  • pituicytes
  • venous blood
  • tissue fluid
  • surrounding CSF

Question 38

Question
What is the effect of ADH?
Answer
  • Increased water resorption in the kidney
  • Decreased water resorption in the kidney
  • Increase in uterine contractions
  • Stimulation of the adrenal glands

Question 39

Question
Oxytocin increases uterine contractions during birth as well as milk ejection during suckling.
Answer
  • True
  • False

Question 40

Question
Drag and drop the correct answers to describe the mechanism of secretion of hormones from the anterior pituitary/adenohypophysis. 1. Specific neural stimuli lead to [blank_start]synthesis[blank_end] and release of [blank_start]hypothalamic[blank_end] hormones. 2. Hypothalamic hormones are released by [blank_start]neuroendocrine[blank_end] cells into blood vessels at the [blank_start]median eminence[blank_end]. 3. The hypothalamic hormones travel down [blank_start]portal blood vessels[blank_end]. 4. The hypothalamic hormones control release of anterior pituitary hormones.
Answer
  • synthesis
  • hypothalamic
  • neuroendocrine
  • paracrine
  • autocrine
  • median eminence
  • pars tuberalis
  • pars distalis
  • portal blood vessels
  • axons of neuroendocrine cells

Question 41

Question
Which part of the pituitary gland receives direct supply from the hypophyseal arteries?
Answer
  • Posterior pituitary/neurohypophysis
  • Anterior pituitary/adenohypophysis

Question 42

Question
Drag and drop the correct labels to describe the vasculature of the pituitary gland.
Answer
  • Supraoptic nuclei
  • Paraventricular nuclei
  • Superior hypophyseal artery
  • Infundibulum
  • Inferior hypophyseal artery
  • trabecular artery
  • Hypophyseal veins
  • Endocrine cells
  • Anterior pituitary/adenohypophysis
  • Posterior pituitary/neurohypophysis

Question 43

Question
Which of the following are secreted by the anterior pituitary/adenohypophysis?
Answer
  • LH
  • FSH
  • ACTH
  • Melanocyte-stimulating hormone
  • Somatotropin/growth hormine
  • Prolactin
  • TSH
  • ADH
  • Oxytocin

Question 44

Question
What do the hypothalamic hypophysiotrophic hormones do?
Answer
  • Stimulate endocrine cells in the anterior pituitary/adenohypophysis to secrete hormones
  • Stimulate the release of hormones from the Herring bodies in the posterior pituitary/neurohypophysis
  • Increase body temperature
  • Initiate reproductive behaviour

Question 45

Question
Drag and drop the correct labels to describe the effect of hypothalamic hypophysiotrophic hormones on the anterior pituitary/adenohypophysis.
Answer
  • Thyrotropin-releasing hormone
  • Dopamine
  • Corticotropin-releasing hormone
  • Gonadotrophin-releasing hormone
  • Growth-hormone releasing hormone
  • Somatostatin
  • Thyrotroph cells
  • Lactotroph cells
  • Corticotroph cells
  • Gonadotroph cells
  • Somatotroph cells
  • Thyroid-stimulating hormone
  • Prolactin
  • Adrenocorticotrophic hormone
  • Luteinising hormone
  • Follicle-stimulating hormone
  • Growth hormone
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