Bacterial Toxin quiz

1. 1[blank_start]Charrin[blank_end] and [blank_start]Ruffer[blank_end] discovered that despite filtering bacteria, fever could still be induced in [blank_start]rabbits[blank_end]

   1. ACharrin
   2. BRuffer
   3. Crabbits
2. 2using antibiotics for bacterial infections is always good to cure disease

   1. ATrue
   2. BFalse
3. 3Vibrio cholerae [blank_start]cannot[blank_end] be treated with antibiotics

   1. Acannot
   2. Bcan
4. 4bacteria can use endotoxins or exotoxins. Exotoxins are made [blank_start]in[blank_end] the bacteria and excreated out into the [blank_start]medium[blank_end] where as endotoxins can only be found in gram [blank_start]negative[blank_end] bacteria in the [blank_start]LPS[blank_end] of the [blank_start]cell wall[blank_end].

   1. Ain
   2. Boutside
   3. Cmedium
   4. Dgut
   5. Enegative
   6. Fpositive
   7. GLPS
   8. HIBS
   9. IPPRs
   10. Jcell wall
   11. Kcytoplasm
   12. Lcell membrane
5. 5Exotoxins are...

   1. Ainsoluble
   2. Blipids
   3. Chighly antigenic
   4. Donly on gram negative bacteria
   5. Esoluble
   6. Fproteins
6. 6which part of bacterium is the endotoxin?

   1. Acore oglisacciharide
   2. Bcell wall
   3. CLipid A
   4. Dpeptidoglycan
7. 7Gram negative [blank_start]sepsis[blank_end] is triggered by [blank_start]endotoxins[blank_end]. They cause systemic [blank_start]inflammatory[blank_end] response. The LPS can be shed from [blank_start]outer[blank_end] membrane [blank_start]vesicles[blank_end] and are resistant to [blank_start]antibiotics[blank_end].

   1. Asepsis
   2. Bfever
   3. Cendotoxins
   4. Dexotoxins
   5. Einflammatory
   6. Fcytokine storm
   7. Gouter
   8. Hinner
   9. Ivesicles
   10. Jpores
   11. Kantibiotics
   12. Lvaccines
8. 8How can exotoxins be used as a virulence factor?
   

   1. Ahelp bacterial spread
   2. Bpromote protein synthesis
   3. Cmodulates the immune system
   4. Ddamage the cell membrane
   5. Einhibition of neurotransmitter
9. 9Exotoxins can cause a cytokine storm known as toxic shock syndrome

   1. ATrue
   2. BFalse
10. 10There are many ways to classify exotoxins. We can divide them into types 1, 2 and 3. Type 1 bind to the [blank_start]surface[blank_end] receptors of the [blank_start]host[blank_end]; type 2 act directly on the [blank_start]cell membrane[blank_end] and type [blank_start]3[blank_end] are known as [blank_start]AB toxins[blank_end]. they make changes by translocating [blank_start]enzymatic[blank_end] components.

    1. Asurface
    2. Bhost
    3. Ccell membrane
    4. D3
    5. EAB toxins
    6. Fenzymatic

11. 11which part of type 3 exotoxins are the active part and which is the binding component?

    1. AA is for binding and B is for activation
    2. BA and B can be used for either binding or activation
    3. CB is for binding and A is for activation
    4. Dthere are no activation and binding components of exotoxins
12. 12describe how AB toxins enter the host cell

    

    1. AB binds to the host cell receptor
    2. BAB enter the cell through a vacuole
    3. Cthe vacuole becomes acidified
    4. DAB dissociate and B exocytose
13. 13AB toxins are a product of a single gene and disulphide bridges exist among them

    1. ATrue
    2. BFalse
14. 14ADP-[blank_start]ribosyltransferase[blank_end] exists both in eukaryotes and bacteria. They act as toxins by [blank_start]removing[blank_end] the ADP-ribose moiety from [blank_start]NAD+[blank_end]. This is then transferred to another [blank_start]molecule[blank_end] to either inactive or activate the [blank_start]cell function[blank_end].

    1. Aribosyltransferase
    2. Btransferase
    3. Ckinase
    4. Dremoving
    5. Eadding
    6. FNAD+
    7. GATP
    8. HLPS
    9. Imolecule
    10. Jcell
    11. Kbacterium
    12. Lcell function
    13. Mimmune system
    14. Ncardiovascular system
15. 15Which bacteria DO NOT have ADP-ribosylation action?

    1. Acholera
    2. Bsalmonella
    3. Ce coli
    4. Dpertussis
    5. Eheliobacter pyori
    6. Fdiptheria
    7. Gyersinia pestis
    8. Hpsuedomonas
16. 16what does vibrio cholerea adhere to before toxins are produced?

    1. Alarge intestine
    2. Brectum
    3. Cblood brain barrier
    4. Dsmall intestine
    5. Esmall intestine mucosa
17. 17Explain cholera's adp-ribosylating toxin (CTX) mechanism of action.

    

    1. Anicked by a bacterial endopeptidase
    2. Bnicked by a bacterial exopeptidase
    3. Cnicked by host endopeptidase
    4. Daddition of phosphate group by kinases
    5. Ebinds to GM1 ganglioside
    6. Fblocks GM1 ganglioside
    7. GBinds to PAMPs
    8. Henters large intestine
    9. Ienters blood stream
    10. Jenters small intestine
    11. Kphosphate is added to g protein
    12. Lg protein inhibited by ADP-ribose
    13. MADP-ribose added to g protein
18. 18what does calcium and sodium enter to cause a high influx of water?

    1. Asmooth muscle
    2. Bintestinal lumen
    3. Cveins
    4. Darteries
19. 19CTX can inhibit EF2 which kills the cell off by inhibiting translation

    1. ATrue
    2. BFalse
20. 20what disease can Bordetella pertussis cause?

    1. Afood poisoning
    2. Bmeningits
    3. Ctyphoid
    4. Dwhooping cough
21. 21PTX is the toxin produced by pertussis. select all the things true of this toxin.

    1. Ait has 4 subunits
    2. Bs1 subunit is cleaved by calmodulin
    3. Cits a ribosyltransferase (S1)
    4. DcAMP is activated to disrupt cell function
    5. Eit doesnt do any of the things listed
    6. Facts on macrophages (S3) and ciliated epithelial cells (S2)
22. 22PTX is produced in it inactive form

    1. ATrue
    2. BFalse
23. 23can diptheria cause disease without its toxin?

    1. Ayes, but it is self limiting
    2. Bno , it is impotent without its toxin
    3. Cyes, only in immunocompromised patients

Description

undergrad biomedical science Quiz on Bacterial Toxin quiz, created by Abbie Adewole on 31/10/2021.

Author

Abbie Adewole

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English

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