Quiz
Neuro Pharmacology - Depression and Anxiety
Questions in this quiz (15)
1Activation of the thalamus can activate the innate fear pathway. Without the collaboration of the prefrontal cortex, this activation can lead to fear manifestations without a source.
- ATrue
- BFalse
2Which of the following statements about the manifestation of anxiety/fear symptoms is not true?
- ALesions of the medical prefrontal cortex increases the risk for anxiety.
- BInhibition of the orbitofrontal cortex leads to the hyperactivity of the amygdala in the presence of a potential threat which produces fear responses.
- CIn the innate fear response, the thalamus is activated by the amygdala with sequential prefrontal cortex activation leading to the fear manifestation.
- DThe amygdala mediates key functions in the processing of fear and threat-related information.
3Select all of the options that are effective in the treatment of anxiety disorder
- ARelaxation Training
- BSystematic Desensitization
- CGroup Therapy
- DPharmacotherapy
4Select the statements about the tuberomamillary nucleus that are true
- AIt is inhibited by GABA from the ventrolateral pre optic area.
- BIt is activated by glutamate
- CIt is inhibited by orexin
- DHistamine promotes calm wakefulness through H2 receptors
5Where to benzodiazepines bind and what is their mechanism of action?
- AThey bind to a niche between the α and γ subunits of the GABAa receptors behaving as GABA agonist
- BThey bing to the niche between the α and γ subunits of the GABAb receptors acting as a positive allosteric modulator
- CThey bind to a niche between the α and γ subunits of the GABAa receptors behaving as positive allosteric modulators
- DThey bing to the niche between the α and γ subunits of the GABAb receptors acting as a GABA agonist
6Positive modulation of the GABAa receptors of the amygdala will produce a hypnotic effect
- ATrue
- BFalse
7Flumenazil is a GABA antaagonist
- ATrue
- BFalse
8Which anti-xiolitic(s) would be a good choice for an elderly patient?
- ALorazepam
- BTemazepam
- CDiazepam
- DChlordiazepoxide
9Drugs binding to α1, α2, α3, α5, and γ subunits of the GABAa synaptic receptor mediate phasic inhibition triggered by peak concentrations of GABA predisposing users to dependence.
- ATrue
- BFalse
10What is the recommended rate of reduction for people wanting to discontinue the use of benzodiazepines?
- AStop immediately and drink a lot of water
- BFlumenazil injections over the course of 5-7 days
- CDecrease by 10 percent each day
- DNone of the above responses are correct
11Barbiturates produce an anti-xiolitic effect by binding to the β subunit of the GABA-a receptor. At high concentrations, they can mimic GABA and directly activate chloride channels.
- ATrue
- BFalse
12Overdose of barbiturates can lead to death due to respiratory and cardiac depression and the lack of an effective antagonist.
- ATrue
- BFalse
13Monoamine Oxidase Inhibitors are Indicated for use with Barbiturates because they shorten the length of action, decreasing side effects.
- ATrue
- BFalse
14What statement below is accurate regarding the changes the amounts of BDNF in the brain of depressed patients?
- AThere is an INCREASE in the amount of BDNF in the Hippocampus and a DECREASE in the amount of BDNF in the Nucleus Accumbens
- BThere is an INCREASE in the amount of BDNF in BOTH the Hippocampus and the Nucleus Accumbens.
- CThere is a DECREASE in the amount of BDNF in BOTH the Hippocampus and the Nucleus Accumbens.
- DThere is a DECREASE in the amount of BDNF in the Hippocampus and an INCREASE in the amount of BDNF in the Nucleus Accumbens.
15Which class of anti-depressants cause the "Cheese Effect"
- AMAOIs
- BSSRIs
- CNMDA Blockers
- DSNRIs
Information
- Description
- KUSOP Pharmacology III "Sample Questions"
- Author
- Ifeoma Okekearu
- Language
- English
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- 114
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