Copy and Edit

Integral Membrane Proteins

Description

Structural Basis for Biological Function (Membrane Proteins) Quiz on Integral Membrane Proteins, created by gina_evans0312 on 14/12/2013.
gina_evans0312
Quiz by gina_evans0312, updated more than 1 year ago
gina_evans0312
Created by gina_evans0312 over 10 years ago
510
1
0

Resource summary

Question 1

Question
5% of the human genome is genes that add a phosphate to something using ATP (Kinases)
Answer
  • True
  • False

Question 2

Question
Which of the following residues can be phosphorylated by kinases?
Answer
  • Serine
  • Threonine
  • Tyrosine
  • Valine
  • Argenine
  • Glutamic Acid

Question 3

Question
How many different kinases are there (roughly)?
Answer
  • 510
  • 520
  • 530

Question 4

Question
In kinases, DFG & RC motifs are highly conserved
Answer
  • True
  • False

Question 5

Question
Which domains are commonly found in kinase interacting proteins?
Answer
  • SH1
  • SH2
  • SH3

Question 6

Question
SH3 proteins mediate the assembly of proteins structures by binding to proline rich peptides in them
Answer
  • True
  • False

Question 7

Question
SH domains modulate protein interactions by recognizing and binding to specific proteins by identifying specific peptide sequences
Answer
  • True
  • False

Question 8

Question
What is the role of PH domains?
Answer
  • Binding the protein to the ER membrane
  • Binding the protein to the cell membrane
  • Binding the protein to nuclear membrane

Question 9

Question
Membranes form what?
Answer
  • Compartments & permeability barriers
  • Compartments & osmotic barriers

Question 10

Question
What mediate membrane functions?
Answer
  • Proteins
  • Glycolipids
  • Phospholipid concentration

Question 11

Question
Mitochondiral membranes contail the most proteins, plasma membranes contain the least (Out of Mitochondrial, Plasma and Myelin membranes)
Answer
  • True
  • False

Question 12

Question
Most integral membrane proteins span the membrane
Answer
  • True
  • False

Question 13

Question
Integral proteins interact extensively with what?
Answer
  • The hydrocarbon chains of lipids
  • The phosphate groups of phospholipids
  • The hydrocarbon tails of phospholipids

Question 14

Question
Peripheral proteins are bound to the membrane via the head groups of phospholipids
Answer
  • True
  • False

Question 15

Question
How do we tell how strongly a membrane protein is associated?
Answer
  • Try and disassociate it using detergent
  • Try and disassociate it using water

Question 16

Question
Baterial Rhodopsin uses heat to pump protons out of the membrane
Answer
  • True
  • False

Question 17

Question
How is the hydrophobic core formed in baterorhodopsin?
Answer
  • 7 alpha helices
  • 7 beta sheets
  • 3 alpha helices, 4 beta sheets

Question 18

Question
In the case of the highly conserved 'Membrane Spanning Alpha Helix Structure', what must be on the outside?
Answer
  • Phospholipids
  • Non-polar aa
  • Polar aa

Question 19

Question
The membrane spanning alpha helix structure acts as what?
Answer
  • A scaffold for the active site
  • The active site
  • The channel for the active site to move through

Question 20

Question
Transmembrane helices can be predicted by a long string (or more) of hydrophobic amino acids in their aa sequence
Answer
  • True
  • False

Question 21

Question
What is used to estimate the free energy change of a residue on transfer of a residue to water (i.e. how much energy does it take to disassociate the aa from the protein)?
Answer
  • A polarity scale
  • An amino scale
  • A pH scale

Question 22

Question
An amino acid with high energy lies buried in a hydrophobic region i.e. the membrane
Answer
  • True
  • False

Question 23

Question
How large is the hydrocarbon core of the membrane?
Answer
  • 30A
  • 32A
  • 34A

Question 24

Question
What is the name of the 20aa section of an integral protein that spans the membrane?
Answer
  • Pocket
  • Window
  • Scaffold

Question 25

Question
How is a Hydropathy plot formed?
Answer
  • The free energy change for each 20 aa segement plotted against the first aa in each segment
  • The free energy change for each 20 aa segement plotted against the last aa in each segment
  • The free energy change for each 30 aa segement plotted against the first aa in each segment

Question 26

Question
What is the point of a hydropathy plot?
Answer
  • To find which aa are in hydrophobic areas
  • To find the window of integral proteins
  • To find the window of peripheral proteins

Question 27

Question
The criterion level for a hydropathy plot is +68
Answer
  • True
  • False

Question 28

Question
What is Porin an example of?
Answer
  • Membrane spanning alpha helices
  • Membrane spanning beta sheets
  • Membrane spanning helix/beta sheet structure

Question 29

Question
What tends to be the features of membrane spanning beta sheet residues?
Answer
  • Hydrophobic
  • Hydrophillic
  • Alternating hydrophobic and hydrophilic

Question 30

Question
The polarity of the internal aa in a membrane spanning beta sheet depends on the size
Answer
  • True
  • False

Question 31

Question
Each sheet in the m.s beta sheet arrangement is hydrogen bonded to its neighbor in a parallel manner
Answer
  • True
  • False
Show full summary Hide full summary

Want to create your own Quizzes for free with GoConqr? Learn more.

Similar

Chemiosmosis
gina_evans0312
Alternative Oxidase
gina_evans0312
Prostaglandin Synthase & Multi-Enzyme Complexes
gina_evans0312
Electron Transport Chain
gina_evans0312
Cyt C Oxidase & F1F0
gina_evans0312
Oxidation Practical
gina_evans0312
Protein Folding- The Basics
gina_evans0312
Molecular Motors- Helicases
gina_evans0312
Constituative Chaperones
gina_evans0312
Chaperonins
gina_evans0312
Heat Shock Proteins
gina_evans0312
Browse Library