CM1512 Jaspar

1. 1The polarity of organic molecules is often low

   1. ATrue
   2. BFalse
2. 2What is the most common acidic group?

   1. ACarboxylic acid
   2. BHydroxide
   3. CCarbonyl
   4. DAmine
3. 3What is the most common basic group?

   1. AAmine
   2. BHydroxide
   3. CCarboxylic acid
   4. DCarbonyl
4. 4Which atom forms hybrid orbitals?

   1. ACarbon
   2. BHydrogen
   3. CNeon
   4. DOxygen
5. 5What is the function of proteins in the body?

   1. AStructure
   2. BProtection
   3. CChemical reactions
   4. DCell signalling
   5. EApoptosis
   6. FEnergy production
6. 6Why are almost all amino acids named 'alpha' amino acids?

   1. AThe amino group is joined to the first carbon next to the carboxylic acid group
   2. BThe amino group is joined to the second carbon next to the carboxylic acid group
   3. CThey are essential for the human body function
7. 7What is a zwitterion?

   1. AA dipolar ion
   2. BA molecule with both a positive and negative charge
   3. CBoth answers
8. 8What is the main property of a amphoteric substance?

   1. ACan act as an acid and a base
   2. BCan only act as an acid
   3. CCan act as a buffer and a base
   4. DCan only act as a base
9. 9The isoelectric point is the point at which the amino acid is exactly balanced between the anionic and cationic forms and is primarily in the neutral or zwitterionic form

   1. ATrue
   2. BFalse
10. 10What is the stereochemistry of all natural amino acids?

    1. AL/ D
    2. BQ
    3. CR
    4. DH

11. 11What is aspartame a source of?

    1. APhenylalanine
    2. BDopamine
    3. CSerotonin
    4. DAcetylcholine
12. 12What did Anfinsen show?

    1. A3D protein structure is dictated by amino acid sequence alone
    2. BAmino acids are able to form hydrogen bonds within molecules
    3. CProteins can fold to form a more stable state
    4. DNone of the above
13. 13The [blank_start]primary[blank_end] structure of proteins is the order of the amino acids in the peptide sequence
    The [blank_start]secondary[blank_end] structure of proteins refers to the types of ordered structures taken up by the protein chain such as the a-helix and b-sheets
    The [blank_start]tertiary[blank_end] structure is the overall 3D shape of the protein

    1. Aprimary
    2. Bsecondary
    3. Ctertiary
    4. Dsecondary
    5. Eprimary
    6. Ftertiary
    7. Gtertiary
    8. Hprimary
    9. Isecondary
14. 14How can the folding pattern of a protein be described?

    1. ADihedral rotation around main bond of chain
    2. BTorsional rotation around main bond of chain
    3. CSehedral rotation around main bond of chain
15. 15In secondary structure of proteins, what must be achieved?

    1. ALow energy conformations of individual residues
    2. BHigh energy conformations of individual residues
    3. CHydrogen bonding by polar groups including buried ones
    4. DDispersion forces by polar groups including buried ones
    5. EFormation of compact and well packed structures
16. 16How is a beta-turn stabilised?

    1. AHydrogen bonds
    2. BIonic bonds
    3. CDispersion forces
    4. DPermanent dipole interactions
17. 17What is propensity?

    1. AThe tendency for any amino acid to appear in a secondary structure type
    2. BThe tendency for any amino acid to appear in a primary structure type
    3. CThe tendency for any amino acid to appear in a tertiary structure type
18. 18What does it mean when propensity values > 1?

    1. AA residue shows a preference for that secondary structure type
    2. BA residue does not favour that structural type
19. 19Which type of interactions play a major role in the stabilisation of tertiary protein structure?

    1. AHydrophobic interactions
    2. BHydrophilic interactions
    3. CHydrogen bonds
    4. DDispersion forces
    5. EIntermolecular forces
20. 20All interactions that stabilize tertiary structure are non-covalent

    1. ATrue
    2. BFalse
21. 21How is the disulfide bond formed?

    1. AA covalent bond forms between two thiol groups of two adjacent cysteine residues
    2. BA hydrogen bond forms between two amine groups of two parallel guanine residues
22. 22What does a Ramachandran plot show?

    1. AThe conformational space a protein is allowed to inhabit
    2. BThe angles of rotation around the main bonds in a protein
    3. CThe number of hydrogen bonds formed in a secondary protein structure
23. 23The quaternary structure describes the way in which the component subunits of a large biological macromolecule assemble to form the fully functioning complex

    1. ATrue
    2. BFalse
24. 24Which criteria must a molecule fufill in order for it to function properly?

    1. AIt must be held in the correct shape
    2. BIt must exhibit structural flexibility
    3. CIt must display a network of covalent bonds that defines the molecular configuration
25. 25Which type of protein in striated muscle controls structural flexibility?

    1. AMyosin
    2. BActin
26. 26What is allostery?

    1. AThe modification in the behaviour of a protein through conformational change triggered by the binding of a molecule to the protein
    2. BThe phenomenon of the movement of atoms within a molecule in order to change it's tertiary structure
    3. CBoth answers
27. 27What are the three classes of carbohydrates?

    1. AMonosaccharides
    2. BDisaccharides
    3. CPolysaccharides
    4. DUnosaccharides
    5. EAll of the above
28. 28Most monosaccharides are cyclic

    1. ATrue
    2. BFalse
29. 29If C=O is attached to terminal carbon in chain then it is an [blank_start]aldose[blank_end]
    If C=O is attached to second carbon atom then it is a [blank_start]ketose[blank_end]
    

    1. Aaldose
    2. Bketose
    3. Cketose
    4. Daldose
30. 30What is the name of the anomer giving 6 membered rings?

    1. APyranose
    2. BFuranose
31. 31What are some examples of disaccharides?

    1. ALactose
    2. BSucrose
    3. CFructose
32. 32What are some examples of polysaccharides?

    1. ACellulose
    2. BStarch
    3. CGlucose
    4. DGlycogen
    5. ESucrose
33. 33Starch cannot be metabolised because it has α-links.

    1. ATrue
    2. BFalse
34. 34Glycogen is branched like amylopectin

    1. ATrue
    2. BFalse
35. 35Lipids are usually the esters of long chain carboxylic acids

    1. ATrue
    2. BFalse
36. 36[blank_start]Saturated[blank_end] – no double bonds
    [blank_start]Monounsaturated[blank_end] – 1 double bond
    [blank_start]Polyunsaturated[blank_end] – more than 1 double bond
    

    1. ASaturated
    2. BMonounsaturated
    3. CPolyunsaturated
    4. DMonounsaturated
    5. ESaturated
    6. FPolyunsaturated
    7. GPolyunsaturated
    8. HSaturated
    9. IMonounsaturated
37. 37What is the function of anadamide?

    1. AIn the brain it interacts with the cannabinoid receptor and plays a role in making and breaking short term neural connections
    2. BPlays a role in the treatment of MS and glaucoma
    3. CBoth answers
38. 38Glycerophospholipids can be found in the cell membrane, but what does this molecule contain?

    1. APhosphodiester
    2. BAmino alcohol
    3. CAmino acid
39. 39Which system is the steroid structure based on?

    1. ATetracyclic
    2. BPyranose
    3. CFuranose
    4. DDuranose
40. 40Which stereoisomer of steroids is the most common?

    1. AA, B trans-fused steroids
    2. BA, B cis-fused steroids
41. 41Select all the examples of important steroids in chemistry.

    1. ACortisone
    2. BTestosterone
    3. CNorethinodrone
    4. DEstradiol
    5. EOestrogen
    6. FAcetylcholine
    7. GNandrolone
    8. HDigitoxigenin
    9. IAnandrol
42. 42When comparing nucleotides and nucleosides, what is missing from nucleosides?

    1. APhosphate
    2. BNitrogenous base
    3. CSugar
43. 43Do purines have a double or single carbon ring?

    1. ADouble
    2. BSingle
44. 44What is the difference between ribose and deoxyribose sugars?

    1. ARibose has an additional hydroxide group
    2. BDeoxyribose has an additional hydroxide group
    3. CRibose has an additional carbonyl group
    4. DDeoxyribose has an additional carbonyl group
45. 45Which type of bond is formed between nucleotides in DNA and RNA?

    1. APhosphodiester
    2. BIonic
    3. CHydrogen
    4. DPermanent dipole bond
46. 46What is the name of tightly packed DNA?

    1. AHeterochromatin
    2. BHomochromatin
    3. CEuchromatin
47. 47What are natural products also known as?

    1. ASecondary metabolites
    2. BPrimary metabolites
    3. CTertiary metabolites
    4. DQuaternary metabolites
48. 48What are terpenes responsible for in plants?

    1. AFragrances
    2. BToxins
    3. CResins
    4. DNone of the above
49. 49What was Epherdra sp first used as?

    1. AImprove circulation
    2. BCough suppressant
    3. CBoth answers
50. 50What is Taxus brevifolia used for in medicine?

    1. AAgainst breast and ovarian cancers
    2. BAgainst respiratory infections
    3. CAppetite suppressant
    4. DAll of the above
51. 51What is the function of taxol?

    1. AActs as mitotic spindle toxin
    2. BAids the transcription process of DNA
    3. CBuilds up cholesterol in the cell wall
52. 52Catharanthus roseus were used in Madagascar as treatment for diabetes and then became a treatment for cancer, as the vinca alkaloids are tubulin binders

    1. ATrue
    2. BFalse
53. 53Which molecule made transplant surgery possible?

    1. ACyclosporin
    2. BReserpine
    3. CPodophyllotoxin
    4. DVincristine

Description

Quiz on CM1512 Jaspar, created by Rhona Cummine on 19/04/2016.

Author

Rhona Cummine

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