Sophie Barrett
Quiz by , created about 5 years ago

Aetiology Pathophysiology Clinical Features Biochemical Tests

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Sophie Barrett
Created by Sophie Barrett about 5 years ago
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Question 1

Question
Jaundice is characterised by a yellow discolouration of the skin and sclera.
Answer
  • True
  • False

Question 2

Question
Which of the following best describes the cause of the colour change seen in jaundice patients.
Answer
  • Too little bilirubin in the skin.
  • Hyperbiliruinaemia
  • Bilirubin getting trapped in the skin and not metabolised.

Question 3

Question
Bilirubin is derived from tetrapyrole prosthetic group found in lymphocytes.
Answer
  • True
  • False

Question 4

Question
Which of the following are the 3 main causes of why bilirubin levels may rise in blood?
Answer
  • Haemolysis of red blood cells.
  • Bilirubin in prescription medications.
  • Failure of the conjugating mechanism.
  • Obstruction in the biliary system.

Question 5

Question
Increased bilirubin production as a result of haemolysis gives...
Answer
  • ...a predominantly unconjugated hyperbilirubinaemia.
  • ...a predominantly unconjugated hypobilirubinaemia.
  • ...a predominantly conjugated hyperbilirubinaemia.
  • ...a predominantly conjugated hypobilirubinaemia.

Question 6

Question
Phototherapy should be offered to babies with jaundice if their bilirubin level approaches:
Answer
  • >200 microlitres per litre.
  • >40 microlitres per litre.
  • >300 microlitres per litre.
  • >100 millilitres per litre.

Question 7

Question
Which of the following best describes the effect of a complete blockage of the bile duct by a gallstone?
Answer
  • Bilirubin and alkaline phosphatae are raised. Little or no urobilinogen in the urine and the stools will be pale.
  • Bilirubin is raised and hence, the stools are dark.
  • Bilirubin urobilinogen are raised, with pale stools and urine.

Question 8

Question
Bilirubin is partly digested by gut bacteria to produce stercobilinogen - this is partly reabsorbed and re-excreted in the urine as urobilinogen.
Answer
  • True
  • False

Question 9

Question
Unconjugated bilirubin is normally bound to albumin, but is water-soluble.
Answer
  • True
  • False

Question 10

Question
Which 2 of the following are the most common causes of jaundice in adults?
Answer
  • Paracetamol Poisoning
  • Viral Hepatitis
  • Excessive Alcohol Consumption.
  • Secondary Neoplasm in the Liver

Question 11

Question
A more unusual cause of jaundice is seen in neonates that have...
Answer
  • been born more than 3 weeks premature.
  • an alpha 1 - antitrypsin defiency (Wilson's Disease).
  • been born to a mother who drunk excessive amounts of alcool throughout pregnancy.