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Endocrinology_2015
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Questions in this quiz (15)
1Which of the following counter-regulatory factors is released earliest in response to hypoglycaemia?
- AA. Adrenaline.
- BB. Cortisol.
- CC. Noradrenaline.
- DD. Growth hormone.
- EE. Glucagon.
2Which of the following has the greatest effect on peak bone mass?
- AA. Pubertal age.
- BB. Childhood calcium intake.
- CC. Genetic factors.
- DD. Childhood physical activity.
- EE. Body weight.
3A 16-year-old male presents with short stature. Which of the following findings is most suggestive of growth hormone deficiency?
- AA. Reduced growth velocity.
- BB. Decreased bone age.
- CC: Height below the 3rd centile.
- DD. Delayed puberty.
- EE. Increased body weight.
4In a normal person, which of the following is most likely to cause a decrease in circulating growth hormone concentration?
- AA. Slow wave sleep.
- BB. Hyperglycaemia.
- CC. Protein meal.
- DD. Exercise.
- EE. Sepsis.
5A patient presenting to the Emergency Department is thought to have acute intermittent porphyria.
Which of the following is most suggestive of an alternative diagnosis?
- AA. Ileus.
- BB. Hypertension.
- CC. Fever.
- DD. Urinary retention.
- EE. Tachycardia.
6In a patient with Type 2 diabetes which of the following co-existing clinical situations is the strongest contraindication to the use of a thiazolidinedione drug?
- AA: Serum creatinine 200µmol/L.
- BB: Proliferative diabetic retinopathy.
- CC: Severe congestive cardiac failure.
- DD: Peripheral vascular disease.
- EE: Fatty liver disease.
7A 65-year-old woman with longstanding rheumatoid arthritis and osteoporosis presents with a mid thoracic crush fracture. She has a history of two previous crush fractures and has been taking alendronate 70mg weekly for three months. She has a normal serum calcium, phosphate, albumin and 25 hydroxy-vitamin D. She has taken prednisolone in the past.
Which of the following treatments is most appropriate for future fracture prevention?- AA. Continue alendronate and add raloxifene.
- BB. Cease alendronate and commence intravenous pamidronate.
- CC. Continue alendronate.
- DD. Cease alendronate and commence strontium ranelate.
- EE. Cease alendronate and commence risedronate.
8In patients with type 1 diabetes mellitus the greatest benefit in using a long-acting insulin analogue is in reducing which of the following?
- AA: Diabetic retinopathy.
- BB: Nocturnal hypoglycaemia.
- CC: Insulin hypersensitivity.
- DD: Preprandial hyperglycaemia.
- EE Microalbuminuria.
9A 25-year-old has adrenocorticotrophic hormone -dependent Cushing’s Syndrome. He has a normal MRI scan of the pituitary fossa. Which of the following is the most useful next investigation?
- AA. High dose dexamethasone suppression test.
- BB. CT scan adrenal glands.
- CC. Petrosal sinus sampling.
- DD. Thoracic CT scan.
- EE. Corticotrophin Releasing Hormone (CRH) test.
10A patient with long standing type 1 diabetes presents has the appearances on fundoscopy shown below.
Which of the following therapeutic strategies is most likely to preserve his long-term vision?
- AA. Tight blood pressure control.
- BB. Aspirin.
- CC. Tight blood glucose control.
- DD. Vitrectomy.
- EE. Pan-retinal photocoagulation.
11A 51-year-old man presents with unstable angina. His mother died at age 58 years as a result of a myocardial infarction and his 48-year-old brother, who smoked heavily and was overweight, survived a heart attack two years previously. After discharge he consults the internet and, when reviewed, expresses concern that he may have familial hypercholesterolemia and that there could be a risk that his son, aged 11 years, may also be at risk of heart attack at an early age.
What finding would give you greatest concern that the patient is correct and that is a need to consider further the possibility that other members of his family are at risk of early onset coronary vascular disease?
- AA. Arcus cornealis.
- BB. Tendinous xanthomata.
- CC. LDL (lowdensity lipoprotein) cholesterol of 7.8 mmol/litre [<3.0 mmol/L].
- DD. Xanthelasma.
- EE. His son’s LDL cholesterol level is 1.5 standard deviations above the mean for 11 year olds.
12A 65-year-old man with a history of paroxysmal atrial tachycardia who has been treated with amiodarone for five years presents with worsening palpitations. Thyroid function tests show the following results:
He is commenced on Carbimazole 10mg tds but fails to improve and three weeks later his thyroid function tests are as follows:
Which of the following is the most likely cause of this patient’s thyrotoxicosis?
- AA. Graves Disease.
- BB. Type 1 (iodine-induced) amiodarone induced thyrotoxicosis.
- CC. Type 2 (inflammatory) amiodarone induced thyrotoxicosis.
- DD. Subacute viral thyroiditis.
- EE. Toxic multinodular goitre.
13In the Western population, body mass index (BMI) has significantly increased over the past 40 years in all age groups. Most of this is accounted for by:
- AA. increased caloric intake.
- BB. increased working hours.
- CC. increased maternal participation in the workforce.
- DD. increased use of passive entertainment.
- EE. decreased exercise.
14In a woman with Graves disease, which of the following is associated with an increased relative risk of developing Graves ophthalmopathy?
- AA. Pregnancy.
- BB. Young age.
- CC. High titre microsomal antibodies.
- DD. Smoking.
- EE. Previous thyroid surgery.
15A 58-year-old smoker presents with a new diagnosis of hypertension. His BP has been difficult to control with levels of 190/110 despite amlodipine 10 mg/day and prazosin 5 mg bd. On examination he has a loud abdominal bruit. His CT scan reveals a 1.5 cm left adrenal mass. Laboratory investigations reveal:
The most likely cause of his hypertension is:
- AA. Conns syndrome.
- BB. phaeochromocytoma.
- CC. essential hypertension.
- DD. renal artery stenosis.
- EE. Cushings syndrome.
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- RACP Endocrinology Quiz on Endocrinology_2015, created by Jeku Jacob on 10/01/2017.
- Author
- Jeku Jacob
- Language
- English
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