CD4 (T-Helper) Cell Polarisation

Description

Year 2 Quiz on CD4 (T-Helper) Cell Polarisation, created by gina_evans0312 on 16/04/2014.
gina_evans0312
Quiz by gina_evans0312, updated more than 1 year ago
gina_evans0312
Created by gina_evans0312 about 10 years ago
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Resource summary

Question 1

Question
Th cells are activated by MHCII and a co-stimulation signal
Answer
  • True
  • False

Question 2

Question
CD4 T-cells are a major source of cytokines after activation
Answer
  • True
  • False

Question 3

Question
Which of the following is a major autokrine stimulator for clonal proliferation of Th cells?
Answer
  • IL2
  • IL3
  • IL4

Question 4

Question
Which of the following is not a factor in CD4 cell polarisation?
Answer
  • Infection type (I.e. does the microenvironment indicate a fungus, a virus?)
  • Amount of antigen/binding strength of antigen
  • 'Dose' of infection

Question 5

Question
Production of cytokines by one type of Th cell, causes the polaristion of native Th cells to the type that produced the cytokines (i.e. Th1 produced cytokines encourage Th1 conversion)
Answer
  • True
  • False

Question 6

Question
During non-infection, which cell is predominant?
Answer
  • Th1
  • Th2
  • Neither, till infection tips the balance

Question 7

Question
Name ways in which the activity of cytokines can be controlled
Answer
  • Short half life- only effect nearby cells
  • Specific receptors prevent unwanted signalling
  • High concentrations needed for cell activation
  • Active destruction by incorrect cells
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