genetic engineering

Somatic cell gene therapy- Body cells

Virus genetically modified to contain functioning copy of gene

GM virus infected into stem cells from bone marrow of the patient

Virus uses reverse transcription to insert the functioning copy of the gene

Stem cells return to the patient. They differentiate into functioning cells

Germ line gene therapy- Embroyonic Stem Cells

Virus genetically modified to contain functioning copy of gene

GM virus infected into zygote of the patient

Virus uses reverse transcription to insert the functioning copy of the gene

Zygote returned to the uterus of patient/partner to the patient to develop into an unaffected offspring

Sourced from bone marrow

Sourced from gamete

Can't pass on allele/ not inherited

Allele can be passed on/ inherited

Target is the patient and needs to be done multiple times

Target is future offspring