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Cell Signalling

J yadonknow Englisch 12 Karten

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  1. 1How can cells communicate?Via extracellular messenger molecules that can travel short distance (stim. cells in close proximity) or long distances (far away from source).
  2. 2What is paracrine?Close release of messenger molecule from secretory cell to adjacent target cell
  3. 3Why is travel of these molecules limited?Unstable
    Fast degradation by enzyme
    Easily sequestered by other molecules, the kuriboh's of the cell.
  4. 4Give an exampleSignalling across neuro-muscular junction
  5. 5What does autocrine mean?Sender and target are on the same cell.
  6. 6What is characteristic about autocrine cells?Short distance
    Seen in developmental staged ells
    Seen in disease process, cancer stimulates its own growth = Autocrine Growth Loop
  7. 7What is endocrine?Usually a distant cells
    Hormones are signalling molecules
  8. 8What is juxtacrine signalling?Signalling cells in direct contact via gap junction/connexons
  9. 9How does a signalling molecule work?Binds to specific receptor
    Ensures specificity of response - lock and key
  10. 10Where can receptors be found?Can be transmembrane, or inside the cell (intracellular)
  11. 11What do transmembrane receptors do for a special type of molecules?if a large water soluble molecule can't pass through lipid bilayer, it binds to transmembrane proteins
  12. 12—

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Karteikarten am Cell Signalling, erstellt von J yadonknow am 18/01/2018.
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