RTKs

fatimaelfitouri
Mind Map by fatimaelfitouri, updated more than 1 year ago
fatimaelfitouri
Created by fatimaelfitouri over 6 years ago
1600
0

Description

cell signalling Mind Map on RTKs, created by fatimaelfitouri on 22/11/2013.
Tags

Resource summary

RTKs
1 Receptor tyrosine kinase (RTK)
2 PDGFR
3 insulin R
4 more than 50 identified
5 single polypeptides except insulin R
6 structure
6.1 transmembrane
6.2 variety of extracellular domain
6.3 Enter text here
6.4 ligand binding domain in the extracellular region
6.5 a single transmembrane helix
6.6 cytoplasmic region containing a protein tyrosine kinase (TK) domian, carboxyl terminal and juxtamembrane regulatory region
7 induction
7.1 ligand binds to receptor= dimerisation of receptor
7.2 dimerisation promotes autophosphorylation
7.3
8 some RTKs form oligmers in the absence of activating ligands eg insulin R and IGF1R
Show full summary Hide full summary

Similar

Cell Signalling Note
gordonbrad
S377 Chapter 13
Mikki M
General Principles I
Joakim Silva
Post-Transcription Activation By CAMP
007842-Stuart Denton
Cytokine receptors
fatimaelfitouri
C1 B1 & P1 Test
jodie00
Calculus I
GraceEChem
Why did the Cold War end?
Elisa de Toro Arias
AWS – Solution Architect Associate Level Certification - Mock Test
stephon
Phrasal Verbs
Felipe Veintimilla
1PR101 2.test - Část 1.
Nikola Truong