Flashcards
Cell Signalling
Flashcards do conjunto (12)
- 1How can cells communicate?Via extracellular messenger molecules that can travel short distance (stim. cells in close proximity) or long distances (far away from source).
- 2What is paracrine?Close release of messenger molecule from secretory cell to adjacent target cell
- 3Why is travel of these molecules limited?Unstable
Fast degradation by enzyme
Easily sequestered by other molecules, the kuriboh's of the cell. - 4Give an exampleSignalling across neuro-muscular junction
- 5What does autocrine mean?Sender and target are on the same cell.
- 6What is characteristic about autocrine cells?Short distance
Seen in developmental staged ells
Seen in disease process, cancer stimulates its own growth = Autocrine Growth Loop - 7What is endocrine?Usually a distant cells
Hormones are signalling molecules - 8What is juxtacrine signalling?Signalling cells in direct contact via gap junction/connexons
- 9How does a signalling molecule work?Binds to specific receptor
Ensures specificity of response - lock and key - 10Where can receptors be found?Can be transmembrane, or inside the cell (intracellular)
- 11What do transmembrane receptors do for a special type of molecules?if a large water soluble molecule can't pass through lipid bilayer, it binds to transmembrane proteins
- 12—
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- FlashCards sobre Cell Signalling, criado por J yadonknow em 18-01-2018.
- Criado por
- J yadonknow
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