T Cell Activation

1) Pathogenic organism present (in the spleen for example)

3) Chemokines

-direct where it should migrate to

4) Lymphocyte Activation: Sticks a little longer

-proper HLA : Antigen fit

4) Produce appropriate cytokines and CLONALLY EXPAND

5) Differentiation: into Effector and Memory CD4+ T helper cells and Effector and Memory CD8+ T cytotoxic cells

BASIC OVERVIEW OF

T CELL ACTIVATION

2) Antigen recognition by APC's

6) Execute Effector Functions depending on Type of T cell