Virology (week 3 and 4)

Beschreibung

DVM2 Virology Quiz am Virology (week 3 and 4), erstellt von Kathryn Borg am 26/04/2016.
Kathryn Borg
Quiz von Kathryn Borg, aktualisiert more than 1 year ago
Kathryn Borg
Erstellt von Kathryn Borg vor etwa 8 Jahre
18
2

Zusammenfassung der Ressource

Frage 1

Frage
Correctly describe the family of Poxviridae
Antworten
  • Large complex structured viruses with a single molecule of ds DNA
  • Large complex structured viruses with a two molecules of ds RNA
  • Large complex structured viruses with a single molecule of ss DNA
  • Small complex structured viruses with a single molecule of ss DNA

Frage 2

Frage
What are the two sub-families within Poxviridae?
Antworten
  • Chordopoxvirinae
  • Entomopoxvirinae
  • Alphaherpesvirinae
  • Papillomavirus
  • Orbivirus

Frage 3

Frage
What is this lesion?
Antworten
  • Pock
  • Pustule
  • Ulceration
  • Macule

Frage 4

Frage
What is the correct pathogenesis of a pock lesion?
Antworten
  • Raised, reddened macule-->papule--> fluid filled vesicle-->Ruptures to form a crater (pock)-->Scarring
  • papule--> Raised, reddened macule--> fluid filled vesicle-->Ruptures to form a crater (pock)-->Scarring
  • fluid filled vesicle-->papule--> Raised, reddened macule-->Ruptures to form a crater (pock)-->Scarring

Frage 5

Frage
What is true of pox viruses?
Antworten
  • Duration of immunity < life span of recovered animal
  • Reinfection possible
  • Surviving animals are NOT long term carriers
  • Infectious virus survives for years in infected material (scabs)
  • Pox viruses are very resistant in the environment
  • Surviving animals ARE long term carriers
  • Pox viruses are labile in the environment
  • Immunity is for life

Frage 6

Frage
Poxvirus transmission between animals may occur by?
Antworten
  • Mechanical transmission
  • Respiratory route by droplets
  • Via abraded skin

Frage 7

Frage
Label this diagram correctly. Matching the correct genus with the virus groups (a-f)
Antworten
  • Orthopoxvirus
  • Parapoxvirus
  • Capripoxvirus
  • Avipoxvirus
  • Suipoxvirus
  • Leporipoxvirus

Frage 8

Frage
What is true of cowpox?
Antworten
  • Rodent reservoir
  • Endemic in Europe and Russia and exotic to Australia
  • Results in pock lesions on teats
  • Can affect humans causing maculopapular lesions on hands and face
  • Can affect domestic and large cats
  • Endemic to Australia
  • Mosquito reservoir

Frage 9

Frage
Sheeppox, Lumpy skin disease and Goat pox are closely related viruses that are indistinguishable by serological assays
Antworten
  • True
  • False

Frage 10

Frage
How might an animal become infected by a Capripoxvirus (sheeppox, lumpy skin disease and goat pox)?
Antworten
  • Skin abrasions
  • Inhalation of aerosols
  • Vector transmission
  • Gastrointestinal tract infection

Frage 11

Frage
Where are the Capripoxviruses (sheeppox, lumpy skin disease and goat pox) endemic to?
Antworten
  • Endemic in SE Europe, Middle East, Africa and Asia
  • Endemic in North America, Northern Europe and Australia
  • Endemic in North America and Australia
  • Endemic in North America, the UK, Africa and Asia

Frage 12

Frage
What is the pathogenesis of the Capripoxviruses (sheeppox, lumpy skin disease and goat pox)?
Antworten
  • Replicates locally in skin
  • Replicates in lungs following inhalation
  • Can spread to regional lymph nodes
  • Replicates in the gut when swallowed
  • Replicates in lymphocytes

Frage 13

Frage
What is the incubation period of the Capripoxviruses (sheeppox, lumpy skin disease and goat pox)?
Antworten
  • ~ 1 week
  • ~ 3 weeks
  • ~ 2 weeks
  • ~ 1 day

Frage 14

Frage
How might fowl pox be transmitted between animals?
Antworten
  • Mechanical transmission via mosquitos
  • Aerosol transmission
  • GIT transmission

Frage 15

Frage
Fowl pox is found within what genus of poxviridae?
Antworten
  • Avipoxvirus
  • Capripoxvirus
  • Orthopoxvirus
  • Parapoxvirus

Frage 16

Frage
What is the Parapoxviruses Orf also called?
Antworten
  • Scabby Mouth
  • Contagious pustular dermatitis
  • Contagious ecthyma

Frage 17

Frage
What is this disease most likely to be if it is from the poxviridae family?
Antworten
  • Orf
  • Bovine Papilloma virus
  • Foot and mouth disease

Frage 18

Frage
What is true of the pathogenesis and epidemiology of Orf?
Antworten
  • Papular lesions progress to vesicles, pustules and then scabs
  • Lesions heal within 4 weeks (if no secondary bacterial infection)
  • Replicates in epidermal keratinocytes
  • Controlled by virulent vaccination
  • Lesions usually on lips and muzzle (feet, genitalia and teats)
  • Maintained in flocks by chronic carriers
  • Transmission via abrasions
  • Primarily a disease of young sheep
  • There are NO carrier animals
  • There is no vaccination available

Frage 19

Frage
What is Myxomatosis?
Antworten
  • A poxvirus disease of rabbits
  • A papillomavirus disease of dogs
  • A poxvirus disease of dogs
  • A poxvirus disease of cats

Frage 20

Frage
Correctly describe the family of Asfarviridae?
Antworten
  • They are complex enveloped double stranded DNA virus
  • They are complex enveloped single stranded DNA virus
  • They are complex non-enveloped double stranded DNA virus
  • They are complex enveloped double stranded RNA virus
  • They are complex non-double stranded RNA virus

Frage 21

Frage
Asfarviridae is Stable in the environment over a wide range of temperatures (4‐20oC) and a wide range of pH. It may persist for months in meat of infected pigs.
Antworten
  • True
  • False

Frage 22

Frage
Which of the below viruses belong to the family Asfarviridae?
Antworten
  • African Swine Fever Virus
  • African Horse Sickness
  • Foot and Mouth Disease (FMD)
  • Contagious pustular dermatitis

Frage 23

Frage
What animals can Asfarviridae infect?
Antworten
  • Soft ticks (Ornithodorus moubata and O erraticus)
  • Suidae (eg. pigs, warthogs)
  • Felidae (Domestic cats, lions, tigers)
  • Bovidae (cattle, ox)
  • Canidae (dogs, wolves)
  • Blow flies (Lucillia cuprina, Calliphora stygia)

Frage 24

Frage
Is a vaccine available for African Swine Fever Virus?
Antworten
  • Yes
  • No

Frage 25

Frage
Where does the virus grow within the body?
Antworten
  • In the reticuloendothelial system
  • In the respiratory sytem
  • In the nervous system
  • In the gastrointestinal system

Frage 26

Frage
Are there carriers of African swine fever virus?
Antworten
  • Yes
  • No

Frage 27

Frage
Why might an animal with African Swine Fever Virus die?
Antworten
  • Extensive haemorrhages in all organs due to platelet damage and complement activation
  • Damage to the CNS causing the lungs to collapse
  • Oedamatous fluid in the lungs

Frage 28

Frage
Describe the Herpesviruses?
Antworten
  • Enveloped double stranded DNA viruses
  • Non-Enveloped double stranded DNA viruses
  • Enveloped single stranded DNA viruses
  • Non-enveloped single stranded DNA viruses

Frage 29

Frage
Why are the herpesviruses labile in environment and easily inactivated by heat, detergents, pH and drying?
Antworten
  • They are enveloped viruses
  • They are non-enveloped viruses
  • They are capsulated viruses

Frage 30

Frage
How are Herpesviruses transmitted?
Antworten
  • Close or mucosal contact for transmission (droplet)
  • GIT transmission
  • Vector transmission

Frage 31

Frage
What is the key feature of Herpesviruses?
Antworten
  • They cause a lifelong latent infection
  • They cause 100% mortality in the infected
  • Infection results in lifelong immunity

Frage 32

Frage
What are the sub families of Herpesviridae?
Antworten
  • Alphaherpesvirinae
  • Gammaherpesvirinae
  • Betaherpesvirinae
  • Deltaherpesvirinae
  • Alloherpesvirinae

Frage 33

Frage
Match the correct virus sub families to their features
Antworten
  • Gammaherpesvirinae
  • Betaherpesvirinae
  • Alphaherpesvirinae
  • Deltaherpesvirinae

Frage 34

Frage
Bovine herpesvirus 1 (Infectious bovine rhinotracheitis virus) can manifest as which of the below clinical diseases?
Antworten
  • Rhinotracheitis
  • Generalised disease of newborn calves
  • Enteritis
  • Abortion
  • Conjunctivitis
  • Balanoposthitis
  • Vulvovaginitis

Frage 35

Frage
How is Bovine Herpesvirus 1 transmitted?
Antworten
  • Respiratory route and cell associated viraemia to distant sites
  • GIT route
  • Fomites
  • Vector transmission

Frage 36

Frage
Bovine herpesvirus 2 -- Bovine mammillitis virus (Pseudo‐lumpy skin disease virus) can cause which of the below forms of clinical disease
Antworten
  • Mammillitis. Lesions localised to the teats.
  • Generalised skin lesions. Nodules & necrosis of the superficial epidermis
  • Abortion
  • Rhinotracheitis

Frage 37

Frage
Bovine herpes virus 5 causes?
Antworten
  • Fatal meningoencephalitis in calves thought to be due to direct neural spread from nasopharynx via trigeminal nerve
  • Respiratory disease, abortion and neurological disease in foals
  • Acute respiratory disease characterised by nasal discharge and lymphadenopathy in calves
  • A variety of clinical diseases

Frage 38

Frage
What is the most important viral cause of abortion in horses worldwide?
Antworten
  • Equine herpesvirus 1
  • Equine herpesvirus 4
  • Bovine herpes virus 1
  • Equine sarcoid virus
  • African horse sickness

Frage 39

Frage
When do abortions usually occur in EHV 1?
Antworten
  • Usually late gestation
  • Usually early gestation
  • Usually mid gestation
  • Abortions do not usually occur

Frage 40

Frage
How can you prevent EHV1 from spreading
Antworten
  • Small groups based on foaling date
  • Pregnant mares be kept separate from other horses
  • There is a vaccine available
  • Cull all animals with the virus

Frage 41

Frage
How long is the aborting mare infectious for?
Antworten
  • 1‐2 days from reproductive tract and up to 2 weeks from the respiratory tract
  • 5-10 days from reproductive tract and up to 6 weeks from the respiratory tract
  • 5‐6 days from reproductive tract and up to 4 weeks from the respiratory tract

Frage 42

Frage
How can EHV1 and EHV4 be differentiated?
Antworten
  • ELISA test for antibody
  • Electron microscopy
  • Viral culture

Frage 43

Frage
Which age group of horses show the most severe clinical signs to EHV4
Antworten
  • Weanling and yearlings (juveniles)
  • Adults
  • Old horses

Frage 44

Frage
Feline herpesvirus 1 (Feline rhinotracheitis) causes?
Antworten
  • acute respiratory disease characterised by nasal discharge, ocular discharge, sneezing, dyspnoea and occasional oral ulcers
  • fatal meningoencephalitis in kittens thought to be due to direct neural spread from nasopharynx via trigeminal nerve
  • abortion of kittens during late gestation
  • generalised skin lesions. Nodules & necrosis of the superficial epidermis

Frage 45

Frage
Gallid herpesvirus 1 is also known as?
Antworten
  • Infectious laryngotracheitis
  • Gallid rhinopneumonitis
  • Gallid encephalitis virus
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