Course
PHSI3012 Exam Prep - Topic 1
Topic 1 - Cancer T1L1 - W01-1 (Assinder) Cell Cycle and Cell Proliferation T1L2 - W02-2 (Napier) Limitless Replicative Potential of Cancer Cells T1L3 - W03-1 (Naylor) Metastasis T1L4 - W03-2 (Naylor) Experimental Modelling of Carcinogenesis In Vivo T1L5 - W04-1 (Mason) Skin Cancer T1L6 - W04-2 (Fraser) Leukaemia T1L7 - W05-1 (Naylor) Epithelial Tumours
Modules (7)
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PHSI3012 01-1 Cell Proliferation
Learning objectives: * Understand the difference between cell growth and proliferation * Describe the major events of the cell cycle * Appreciate the roles of cyclins and cyclin-dependent kinases in regulating cell cycle progression * Provide examples of disordered signaling in cancer * Describe checkpoints and how they regulate the correct expression of the cell cycle * Understand the role of apoptosis in preventing inappropriate cell proliferation
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PHSI3012 02-2 Limitless replicative potential of cancer cells
PHSI3012 02-2 Limitless replicative potential of cancer cells Content: * Hallmarks of Cancer * Cellular proliferation * Mortality vs immortality * Telomeres * Telomerase * ALT
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PHSI3012 03-1 Metastasis
Overview: - Overview of metastasis - Define each of the general stages of metastasis - Provide some examples of genes involved in each stage - Different metastasis models - Examples of therapeutic options
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PHSI3012 03-2 Experimental Modelling of Carcinogenesis In Vivo
Overview: - Analysis of cell phenotypes associated with cancer - Analysis of cancer cell phenotypes in vivo - Modelling metastasis - Mouse models of epithelial carcinogenesis - Survival and cross-sectional analysis - Modelling therapeutic treatment
| Course resource | Original resource | Created by |
|---|---|---|
| PHSI3012 01-1 Cell Proliferation | PHSI3012 01-1 Cell Proliferation | Michael Jardine |
| PHSI3012 02-2 Limitless replicative potential of cancer cells | PHSI3012 02-2 Limitless replicative potential of cancer cells | Michael Jardine |
| PHSI3012 03-1 Metastasis | PHSI3012 03-1 Metastasis | Michael Jardine |
| PHSI3012 03-2 Experimental Modelling of Carcinogenesis In Vivo | PHSI3012 03-2 Experimental Modelling of Carcinogenesis In Vivo | Michael Jardine |
| PHSI3012 04-1 Skin Cancer | PHSI3012 04-1 Skin Cancer | Michael Jardine |
| PHSI3012 04-2 Leukaemia | PHSI3012 04-2 Leukaemia | Michael Jardine |
| PHSI3012 05-1 Epithelial Tumours | PHSI3012 05-1 Epithelial Tumours | Michael Jardine |