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Flowchart

Metabolic syndrome: pathophysiology and mechanisms

David Sepúlveda Spanish

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  1. Hyperplasia and hypertrophy of tissue

  2. Alteration of free fatty acid (FFA) metabolism

  3. Impaired adipokine release

  4. FFA

  5. Increased lipoprotein synthesis

    Increased gluconeogenesis

  6. Hyperinsulinemia and insulin resistance

  7. Pancreatic cell dysfunction

  8. Dyslipidemia

  9. Hyperglycemia over T2DM

  10. Activate SRAA and SNS

  11. Vasoconstriction due to sodium reabsorption

  12. Hypertension

  13. Endothelial dysfunction due to oxidative stress

  14. Pro-inflammatory state

    Prothrombotic state

  15. Hypercoagulable state

  16. Metabolic syndrome

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Flowchart on Untitled, created by David Sepúlveda on 13/06/2021.
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