Flashcards
Quiz 1: GI - all EC slides (Lasku)
Cards in this deck (26)
- 1—* [Barrett's Esophagus] *
The two endoscopic views demonstrate Barrett Esophagus areas of mucosal erythema of the lower esophagus, with islands of normal pale esophageal squamous mucosa. - 2—* [Barrett's Esophagus] *
Gastric-type mucosa above the gastroesophageal junction. Note the columnar epithelium (left) and squamous epithelium (right). This is "typical" as there is intestinal metaplasia as well. Left: see goblet cells in the columnar mucosa. - 3—* [Esophageal Varices] *
Pict. in lower esophagus (turned inside out). Varices are linear dark blue submucosal dilated veins prone to bleeding. In portal HTN pts (typ. micronodular cirrhosis from chronic alcoholism), the varices become dilated. - 4—Eosinophilic Esophagitis
- 5—Eosinophilic Esophagitis
- 6—* [Esophageal Sq. Cell Carcinoma] *
An irregular reddish, ulcerated exophytic mid-esophageal mass on the mucosal surface. Endoscopy shows the tumor is causing lumenal stenosis. Risk factors for esophag. SC carcinoma incl smoking & alcoholism (U.S.); or diet (global). - 7—* [Esophageal Sq. Cell Carcinoma] *
Upper left: the mid-esophageal squamous esophageal mucosa has been infiltrated & separated by SCC. Right: Solid nests of neoplastic cells are infiltrating down thru the submucosa. Surgical removal is difficult as Esophageal cancers often metastasize. - 8—* [Acute Gastritis] *
This is a more typical acute gastritis with a diffusely hyperemic gastric mucosa. There are many causes for acute gastritis: alcoholism, drugs, infections, etc. - 9—*[Chronic Gastritis -- Pernicious Anemia]*
With Chronic Atrophic Gastritis autoantibodies block or bind Intrinsic Factor (IF). Also shown here are anti-parietal cell auto-antibodies. Bright green immunofluorescence is seen in the gastric mucosa parietal cells. - 10—* [Peptic Ulcer - Gastric] *
ALL gastric ulcers are biopsied since gross inspection alone cannot determine whether a lesion is malignant. Note that smaller, more sharply demarcated ulcers are more likely to be benign. - 11—* [Peptic Ulcer - Gastric] *
Microscopically, the ulcer here is sharply demarcated, with normal gastric mucosa on the left falling away to the right into a deep ulcer whose base contains inflamed, necrotic debris. An arterial branch at the ulcer base is eroded and bleeding. - 12—Gastric Adenocarcinoma
CANCER
Signet Ring Cells - 13—* [Pseudomembranous Colitis] *
Pseudomembrane is composed of inflammatory cells, necrotic epithelium, and mucus in which the microorganism overgrowth occurs. - 14—* [Celiac Sprue] *
Normal (left); Celiac Sprue (right) showing blunting and flattening of villi. - 15—* [Crohn's Disease] *
Bowel has a thickened wall and the mucosa has lost the regular folds. - 16—* [Crohn's Disease] *
Fistula formation. - 17—* [Ulcerative Colitis] *
Pseudopolyps are the remaining islands
of eroded mucosa. - 18—* [Ulcerative Colitis] *
UC is confined to the mucosa which is eroded by an ulcer that undermines the surrounding mucosa. - 19—* [Ischemic Bowel Disease] *
Mucosa shows marked hyperemia due to the ischemic enteritis - 20—* [Colonic Diverticula] *
Shown along a descending colon piece. - 21—* [Internal Hernia] *
Forceps extend through an internal hernia. - 22—* [Cecal Volvulus] *
Common in adults, in small intestine and colon equally occurring. In very young children it occurs usually in the small intestine. - 23—* [Tubular Adenoma] *
Benign. Is crowded, disorganized, and with less goblet cells compared to the normal colonic mucosa underneath. Polyp also has HYPERchromatic nuclei. - 24—* [FAP - Familial Adenomatous Polyposis] *
Presents as a carpet of small adenomatous polyps. Has 100% risk to become an ADENOCARCINOMA.
Tx is a total colectomy done by age 20. - 25—* [Colorectal Carcinoma] *
the adenocarcinoma is encircling.
From the rectosigmoid region. - 26—* [Acute Appendicitis] *
With yellow to tan exudate and hyperemia, incl the peri-appendiceal fat superiorly, rather than a smooth, glistening pale tan serosal surface.
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- Description
- Extra Credit Gi part 1 = PPT slides 1-62 GI part 2 = PPT slides 63-184 (end)
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- Dez Neb
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