Flashcards
Lecture 6 - Inflammation
Cards in this deck (6)
- 1What is the purpose of inflammation ?TO : - Destroy the pathogen or cellular debris
- Dilute
- Isolate healthy cells from injured cells
- Initiate repair
o Regeneration/proliferation
o Fibrosis (scarring) - 2What are the stages of acute inflamation1. Transient contraction followed by dilation
2. Increased permeability in the microvasculature resulting in exudation
3. Neutrophil accumulation - 3What are the roles of NOVascular muscle relaxation and vasodilation
-Killing of microbes in activated macrophage
- Counteracts platelet adhesion, aggregation and degranulation - 4What is the role of histamineo Pre-formed in mast cells and released by stimulation
o Cause vasodilation and venular endothelial cell contraction - 5Which chemicals are involved immediate vasodilation which on long lastinghistamine and brandikynin is brif through endothelial contraction.
IL-1, TNF cytoskeltal reorganisaiton - 6How does the process of chemo-taxisLeukocytes utilise chemotaxis inorder to move to a site of injury. Chemotaxis involves the use of a chemical gradient from compliment , C5 , cytokines etc . Leukocytes extend psuedopods with adhesion molecules activating leuckocytes. Activation causes preparation AA metabolites , dengraulation
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- UNIVERSITY OF MELBOURNE PATH30001 (Inflammation - Lecture 6 ) Flashcards on Lecture 6 - Inflammation , created by reesha.cornelio1 on 09/06/2015.
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