Created by gina_evans0312
about 10 years ago
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Question | Answer |
Antibiotic Class | Class 2 (Substrates for Macromolecule Production) |
Target (System) | Folic acid synthesis |
Requirement of Target | Required to make DNA |
Selective Toxicity | Humans get folic acid from the diet, bacteria use PABA to make it |
Main Target (Enzyme) | Dihydropterase Synthase, which are inhibited by Sulphinomides |
Dihydrofolate Reductase | Present in human cells but structured differently |
Drug for Dihydrofolate Reductase | Trimethoprim |
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