Acute Phase Reactant

Acute Phase Reactant

1. A substance in the blood that increases as a response to an acute conditions such as infection, injury, tissue destruction, some cancers, burns, surgery, or trauma

2. Important Acute Phase Reactant

   • erythrocyte sedimentation rate (ESR)
     • C-reactive protein (CRP)
       • fibrinogen and ferritin

3. Inflammatory Cells

4. Major APR

   • C-reactive Protien
     • Serum Amyloid P Component
       • Serum Amyloid A Component

5. Haptoglobin

   • Ceruloplasmin
     • Alpha-antitrypsin A
       • Fibrinogen
         • C3

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