1655958
Description
Mind Map by Kristi Brogden, updated more than 1 year ago
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Created by Kristi Brogden
over 10 years ago
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GPCR signalling and structure
- Structure
- Provides clues
to complexity
of signalling
- And hope for
development of
new theraputics
- And hope for
development of
new theraputics
- Comparison
of four GPCR
structures
- Provides clues
to complexity
of signalling
- GPCR
engineering
- Yields high resolution
structural insights into
receptor function
- Why did it take 15+
years to crystalize and
solve a GPCR structure?
- Why did it take 15+
years to crystalize and
solve a GPCR structure?
- Rhodopsin
vs other
GPCR's
- Yields high resolution
structural insights into
receptor function
- GPCR structure predicts
- Complexity in function
- Agonist biased signalling
- Complexity in function
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