Malaria Infection

Malaria Infection

1. Cause

   • Paracite: Plasmodium Sp.
     • mosquito
     • Lysing of Liver and Red blood cells
     • Cycle in Host
   • Transmission via: Mosquito Vector (Anopheles sp.)

2. Treatment

   • Quinoline
   • Aretemisinin-based Combination Therapies (ACT)
   • Vaccines (future)
     • RTS,S
       • 59% efficacy
     • PfSPZ Vaccine
       • 100% efficacy
   • Chlororquine
   • Hydroxychloroquine

3. Prevention

   • Insectacides
     • Bed nets
     • Dichlorodiphenyltrichloroethane (DDT)
     • Dieldrin
     • fenitrothion
   • Gentetic Modification (future)
     • GM Mosquitos
     • GM microbs
   • Immunity
     • Previously infected hosts by uncomplicated Malraia
     • Vectors immune to insectacides
       • Dieldrin

4. Diognosis

   • Symptoms
     • Headache
     • Muscle pain
     • Chills
   • Signs
     • Vommiting
     • Diaherria
     • Anemia
     • Sweats
     • Fever
     • Pale skin
     • Breathing problems

5. Effect

   • Seizures
     • Cerebral Malaria
   • Organ failure
     • Liver
     • Spleen
     • Kidneys

6. Regulation

   • Stockholm Convention 2004: Persisitent Organic Pollutants (POPs)
     • Indoor Residual Spray (IRS)
   • FP7 European Union
     • NANOMAL Project
   • WHO: Initiative for Vaccine Research (IVR)