Neurotransmitter - created from Mind Map

Acetycholine AcH (PRE & PARA POST)

Norephephine NE (SYM POST)eprinephine

Pre-ganlionic axons Synapse @ 1st sym --> ^or v paravert ganglion continue to prevertebral Extend or terminate @ adrenal medulla

Adrenoceptors α (1,2) β (1,2,3) Blood Vessel Heart Constriction Dilation Thrombocytes ^ contractibility Bronchi Aggregation Kidney Dilation Adipocytes Vasoconstriction Renin release (X tubular Na reabsorb) Inhibit lipolysis Lipolysis (triglycerides--> 3 fatty acid + glycerol

Sympathomimetics direct on a &β indirectly on pre-syn terminal Agonist Antagonist X selective Adrenaline α selective β 2 B P + Bronchi Dil Vasopressor Anaphlatic shock treatment 1- nasal decongestant 2 hypotensive drugs Phenylephrine Ephedrine clonide methyldopa Salbutamol β1 Propanolol Atenolol

Cholinomimetics on recpetor Muscarinic Pilocarpine Amanita Muscaria 菇

mimic norepinephine and epinphrine

+reduced BP

a type of allergy, cause death

Dilate bronchial smooth muscle used as aerosol for Asthma if not selective, +heart side effect

Side effect: Bronchial constriction CardioVascular app: H. fail,                                     Stage fright                                    Hypertension                                   Angina                                   Cardiac arhythmias

Eye drop intraocular pressure - for glaucoma 青光眼

BP v 口水 淚水 汗＋ adominal pain, nausea death due to H & lung failure

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Neurotransmitter

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