Flashcards
Ampicillin
Cards in this deck (13)
- 1Trade namesAmpicyn - Ibimycin - Austrapen
- 2Chemical nameAminobenzylpenicillin
- 3Therapeutic classanti-infective
- 4Pharmacological classantibiotic- penicillin
- 5IndicationsChronic bronchitis
CAP (community acquired pneumonia)
Gonnococal infection
Broad spectrum - 6ActionsBactericidal; interfere with bacterial cell wall peptidoglycan synthesis by binding to penicillin-binding proteins, eventually leading to cell lysis and death.
- 7Pharmacokinetics (absorption)Not well absorbed in GIT - best given IV for absorption
- 8DistributionDoes cross placenta and enter breast milk - however is reportedly safe according to AMH
- 9Metabolism & excretionpartially metabolised in the liver, with the remainder of the drug excreted through the kidneys in urine
- 10Contraindications & precautionsPenicillin allergy!
Those with heart failure or on sodium restriction - high levels of sodium
Immunocompromised individuals = high incidence of rash
Renal impairment - 11Adverse reactionsSkin: rash GIT: diarrhoea, N + V, CNS: neurotoxicity at high doses/ renal impairment
- 12Assessment requirementsObtain specimen for culture
Baseline vital signs
Monitor person's response to administration - 13EducationTell patients to report adverse effects and the drink lots of fluids, and keep up nutrition.
Information
- Description
- User has deleted their subject information Flashcards on Ampicillin, created by Deleted user on 04/06/2018.
- Created by
- Deleted user · Jun 2018
- Updated
- Jun 4, 2018
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- History
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- Created by Em J · Jun 3, 2018
- Copied by Em J · Jun 4, 2018
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