BP revisited

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BPrevisited

Describe the actions of the various systems which influence BP in the mammal

BP

Normal BP for

Dog

Cat

Impact of a persistently high BP

Impact of a persistently low BP

Pa = CO xTPR

Factors increasing SV

ESVV + EDVV

High HR

Pathological

Physiological

Control of blood flow

Intrinsic mechanisms control blood flow

Metabolic auto regulation

Paracrine control

Extrinsic mechanisms > intrinsic

Preserve flow to essential tissues

Baroreflex

Receptors in aortic arch + carotid sinuses

Send input to CV centre in medulla oblongata

APs in response to stretch

Inc Bp = Inc freq APs

Compares w reference value

Dec Bp = baroreflex

Output via ANS

RAAS

ADH

Thirst

Outline the role of the kidney in managing blood pressure

Explain how cardiomyocyte contractility can be influenced at a cellular level

Explain how vascular smooth muscle contraction can be influenced at a cellular level